Results 41 to 50 of about 25,612 (261)

Microbiota-dependent TLR2 signaling reduces silver nanoparticle toxicity to zebrafish larvae

Ecotoxicology and Environmental Safety, 2022
Many host-microbiota interactions depend on the recognition of microbial constituents by toll-like receptors of the host. The impacts of these interactions on host health can shape the hosts response to environmental pollutants such as nanomaterials ...
Bregje W. Brinkmann, Bjørn E.V. Koch, Willie J.G.M. Peijnenburg, Martina G. Vijver   +3 more
doaj   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

NAG-1/GDF15 Transgenic Mouse Has Less White Adipose Tissue and a Reduced Inflammatory Response

Mediators of Inflammation, 2013
NAG-1/GDF15 is a TGF-β superfamily member with poorly characterized biological activity proposed to inhibit inflammatory cytokine production. Transgenic mice expressing human NAG-1/GDF15 (NAG-1Tg/Lox) are leaner with lower body weight and are resistant ...
J. M. Kim, J. P. Kosak, J. K. Kim, G. Kissling, D. R. Germolec, D. C. Zeldin, J. A. Bradbury, S. J. Baek, T. E. Eling   +8 more
doaj   +1 more source

Titanium Implant Surface Modification in Physiological Serum Containing New Mixed Inhibitor Based on Poly(vinyl) Alcohol/Silver Nanoparticles/Epirubicin

International Journal of Electrochemical Science, 2018
The titanium behaviour in physiological serum blank (PS) and containing silver nanoparticles (nAg) and polyvinyl alcohol (PVA) in the absence and presence of epirubicin cytostatic (EPR) was studied by potentiodynamic polarization and electrochemical ...
Adriana Samide, Simona Iordache, Gabriela Eugenia Iacobescu, Cristian Tigae, Cezar Spînu   +4 more
doaj   +1 more source

The Use of Bone Void Fillers May Not Impact Outcomes After Medial Opening Wedge High Tibial Osteotomy: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To examine whether the use of bone void filler significantly influences outcomes of medial opening wedge high tibial osteotomy (OWHTO), with a specific emphasis on gap sizes less than 10 mm. Methods A systematic review of the literature was performed according to Preferred Reporting Items for Systematic Reviews and Meta‐Analysis guidelines ...
Travette Daniel, Stephen Medearis, Emily Jones, Victoria K. Ierulli, Mary K. Mulcahey   +4 more
wiley   +1 more source

Characterization of the fate of primary and re-precipitated silver nanoparticles in lake water model systems

Frontiers in Environmental Chemistry
The increasing use of silver nanoparticles (nAg) in products and associated releases to the environment necessitates a thorough understanding of the environmental fate and transformations of these potentially toxic nanomaterials to inform environmental ...
Sarayu Rao, Xiaoyu Gao, Xiaoyu Gao, Subhasis Ghoshal   +3 more
doaj   +1 more source

THE KI-A-NAG OF ENENTARZI

Orient, 1985
In this paper I shall discuss the ki-a-nag (the libation place for the dead) of the Pre-Sargonic Lagas, especially the ki-a-nag of Enentarzi who was the first ruler of the new dynasty after that of Urnanse. We have many records about ki-a-nag in the administrative-economic archives of the e-mi (the house of the wife (of the ruler)).
openaire   +3 more sources

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

Biotechnology and Bioengineering, EarlyView.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse, Monia Ranalli, Drenka Trivanovic, Irina Maslovaric   +3 more
wiley   +1 more source

Characterization of feline nonsteroidal anti-inflammatory drug activated gene-1 (fNAG-1) and its protective function in kidney cells

BMC Veterinary Research
Background Domestic cats are susceptible to obesity and chronic renal failure, leading to significant health risks. Nonsteroidal anti-inflammatory drug-activated gene (NAG-1), also known as growth differentiation factor 15 (GDF15), is a member of the ...
Pattawika Lertpatipanpong, Hyunjin Moon, Jung Eun Seo, Minsu Kim, Seung Joon Baek   +4 more
doaj   +1 more source