KIM-1 as a Biomarker in Genitourinary Neoplasms. [PDF]
Cancers (Basel)Kidney Injury Molecule-1 (KIM-1), a type I transmembrane glycoprotein, is emerging as a promising biomarker in the landscape of genitourinary malignancies. Initially it was described for its role in renal tubular injury, but it is currently being studied for its expression in various neoplasms, particularly renal cell carcinoma, where it correlates ...
Veros C, Bamias A.
europepmc +2 more sources
Urinary NGAL and KIM-1 in Canine Monocytic Ehrlichiosis. [PDF]
Vet SciGlomerulonephritis, caused by the deposition of immune complexes, can lead to kidney damage in dogs with canine monocytic ehrlichiosis (CME). The early diagnosis of renal insult is important to prevent severe kidney disease in infected dogs by Ehrlichia canis.
Pereira ME +13 more
europepmc +4 more sources
Glycemic Variability and KIM-1-Induced Inflammation in the Diabetic Kidney. [PDF]
Diabetes, 2021 Diabetes, the “other pandemic,” has progressively increased in magnitude despite advances in knowledge about diabetes prevention over the last two decades (1). Therefore, diabetes will remain a major public health problem for the foreseeable future.
Tuttle KR, Alicic RZ.
europepmc +4 more sources
Practical Laboratory Medicine, 2019 Objectives: To determine whether pre-existing nephropathy impacts urinary KIM-1 levels, urinary KIM-1 were measured in patients with normal kidney filtration function but either with or without proteinuria.
Edward Randell, Yuan Tian, Yun Huang
exaly +3 more sources
Novel Homo-SELEX for selecting universal aptamer for cross-species kidney injury biomarker KIM-1 in muti-scenario situ imaging [PDF]
Journal of NanobiotechnologyKidney injury molecule 1 (KIM-1) has emerged as a critical biomarker for renal injury, playing a pivotal role in disease diagnosis and therapeutic monitoring.
He Yang +10 more
doaj +2 more sources
From acute tubular injury to tubular repair and chronic kidney diseases – KIM-1 as a promising biomarker for predicting renal tubular pathology [PDF]
Current Research in PhysiologyKidney Injury Molecule-1 (KIM-1) has emerged as a significant biomarker and mechanistic player in kidney pathology, particularly in acute kidney injury (AKI).
Ping L. Zhang, Ming-Lin Liu
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Urinary Kim-1 Correlates with Interstitial Nephritis Activity in Patients with Microscopic Polyangiitis [PDF]
Current Issues in Molecular BiologyBackground: Microscopic polyangiitis (MPA) is a type of necrotizing vasculitis that primarily affects small vessels and belongs to the spectrum of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs).
Chisato Ashida +6 more
doaj +2 more sources
Direct scavenging of ROS by S-PPE NP reduces oxidative stress-induced stimulation of the SESN2/AMPK/KIM-1 pathway in acute kidney injury [PDF]
Renal FailureBackground Previous research demonstrated that treatment of acute kidney injury (AKI) with the antioxidant S-PPE NP reduced the levels of the oxidative stress-responsive protein Sestrin2 (SESN2), and suggested that kidney injury molecule 1 (KIM-1) could ...
Chen Jiao +5 more
doaj +2 more sources
Effects of oleanolic acid administration on renal NF-κB/IL-18/IL-6 and YKL-40/KIM-1 pathways in experimental diabetic rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Neuropathy, retinopathy, and nephropathy, known as the triopathy of diabetes, are the consequences of microvascular complications of diabetes.
Hatice Iskender +5 more
doaj +1 more source
KIM-1 and NGAL: new markers of obstructive nephropathy [PDF]
Pediatric Nephrology, 2011 Congenital obstructive nephropathy is the primary cause of chronic renal failure in children. Rapid diagnosis and initiation of the treatment are vital to preserve function and/or to slow down renal injury. The aim of our study was to determine whether urinary (u) kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL ...
Wasilewska, Anna +4 more
openaire +4 more sources