Results 31 to 40 of about 822,225 (257)
Archives of Clinical and Experimental Surgery, 2016 Objective: The objective of this study is to evaluate whether levels of urinary kidney injury molecule-1 (KIM-1) are increased in patients in different stages of hydronephrosis and to follow the course of the KIM-1 levels after ureterorenoscopy (URS ...
Lokman Irkilata +9 more
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The diagnostic importance of the new marker KIM-1 in kidney damage
Postępy Higieny i Medycyny Doświadczalnej, 2013 In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed. The experimental tests carried out on animals and cell lines derived from the proximal tubule have made ...
Zofia, Marchewka, Joanna, Płonka
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KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression
Postępy Higieny i Medycyny Doświadczalnej, 2016 On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness.
Zofia, Marchewka +2 more
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Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. The determination of nephrotoxicity markers is a useful and necessary step in the detection of renal injury in animal experiments; these markers help accurately localise organ damage.
M. V. Miroshnikov +5 more
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The Effects of Febuxostat on Urine NGAL and Urine KIM-1 in Patients with Hyperuricemia
Journal of Healthcare Engineering, 2022 Retrospective analysis of the effects of febuxostat on urine neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in patients with hyperuricemia was performed. From January 2018 to June 2018, there were 45 patients with asymptomatic hyperuricemia in the outpatient or inpatient of Changzhou Second ...
Yushang Tang +3 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The KIM-1 microcomputer as an eight-channel data logger [PDF]
Behavior Research Methods, Instruments, & Computers, 1984 A machine language program and interface hardware to operate the KIM-1 microcomputer as an eight-channel data logger are described. All channels can operate simultaneously, and the data are stored in a specified area of memory. Double precision is used, enabling numbers greater than 255 to be recorded. Data can be collected over sampling intervals of 1
D. James Campbell, John Forest
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Evaluation of KIM-1 as an early biomarker of snakebite-induced AKI in mice [PDF]
Toxicon, 2018 Acute kidney injury (AKI) is one of the most important complications of bothropic poisoning and its early identification remains challenging. The nephrotoxicity of Bothrops insularis venom (BinsV) was previously described by our research group. In this study, we continued to evaluate the effect of BinsV on kidney function in mice and LLC-MK2 proximal ...
Rodrigo Tavares Dantas +7 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source