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Novel early markers of chronic kidney disease
Pediatria i Medycyna Rodzinna, 2019 Chronic kidney disease is an irreversible kidney damage caused by structural or functional renal impairment and persisting for more than 3 months. It is usually accompanied by albuminuria, proteinuria, abnormal histopathological and imaging findings as ...
Anna Bujnowska +3 more
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JCRPE, 2021 Objective:Neutrophil gelatinase-associated lipocalin (NGAL) is one of the new biomarkers for detecting acute renal injury. There are studies showing the relationship between NGAL and renal injury in obese children.
Semra Şen +7 more
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A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1 (KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo [PDF]
Cancer Research and Treatment, 2019 This study was carried out to identify a peptide that selectively binds to kidney injury molecule-1 (KIM-1) by screening a phage-displayed peptide library and to use the peptide for the detection of KIM-1overexpressing tumors in vivo.Biopanning of a phage-displayed peptide library was performed on KIM-1-coated plates.
Haque, Md. Enamul +8 more
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CRISPR/Cas9 engineering of a KIM-1 reporter human proximal tubule cell line. [PDF]
PLoS ONE, 2018 We used the CRISPR/Cas9 system to knock-in reporter transgenes at the kidney injury molecule-1 (KIM-1) locus and isolated human proximal tubule cell (HK-2) clones. PCR verified targeted knock-in of the luciferase and eGFP reporter at the KIM-1 locus.
Ruth Ann Veach, Matthew H Wilson
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The Predicted Value of Kidney Injury Molecule-1 (KIM-1) in Healthy People
International Journal of General Medicine, 2022 Shanshan Peng,1 Na Liu,1 Kai Wei,1 Gang Li,2 Zheng Zou,3 Tao Liu,3 Meifang Shi,3 Yuan Lv,1 Yong Lin1 1Department of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Shanghai Baoshan Renhe Hospital, Shanghai,
Peng S +8 more
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KIM-1 driving chronic kidney disease [PDF]
Science-Business eXchange, 2013 Harvard researchers have shown that KIM-1, a protein that helps overcome acute kidney injury, can also trigger chronic kidney disease. Companies modulating the target need to scrutinize the therapeutic window of their molecules.
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The role of osteopontin, KIM-1, and fetuin-A as prognostic markers for cardiovascular disease in patients with chronic kidney disease: A systematic review and meta-analysis [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Chronic kidney disease (CKD) is often related to cardiovascular disease (CVD) as a consequence of the progressive nature of the disease. The role of osteopontin (OPN), kidney injury molecule-1 (KIM-1), and fetuin-A in predicting the risk of ...
Yongki Welliam +6 more
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OrganoidsThis review aims to highlight how the study of kidney organoids combined with proteomic analysis can deepen our understanding of renal physiology and disease. Proteomics quantifies proteins in a sample, allowing us to determine which proteins are present,
Kathrin Groeneveld, Ralf Mrowka
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Effectiveness of Motivational Dental Care Interventions for Students in Vietnam
Dentistry JournalBackground: The prevalence of oral diseases in Vietnam has remained high in recent years, especially dental caries and gingivitis. Conventional dental education in schools is ineffective in maintaining good behavior.
Bau Minh Trinh +2 more
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Screening of early diagnostic markers of gentamicin-induced acute kidney injury in canines
Journal of Veterinary Research, 2019 The value of neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (Kim-1), and liver-type fatty acid binding protein (L-FABP) was assessed in early diagnosis of gentamicin-induced acute kidney injury (AKI) in dogs.
Zheng Jia-San +5 more
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