Results 141 to 150 of about 56,585 (261)

Case Report: Upadacitinib for Acrodermatitis continua of Hallopeau: a case series with literature review. [PDF]

Front Immunol
Gan YT, Yan S, Xie WN, Liu Y, Chen FL.
europepmc   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Nailing approach and residual fracture gap: A comparative study of antegrade versus retrograde fixation in distal femoral shaft fractures. [PDF]

Ulus Travma Acil Cerrahi Derg
Onder M, Dogan B, Kayis G, Seluk S, Pehlivanoglu G, Akpinar E, Albayrak K.   +6 more
europepmc   +1 more source

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

Advanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian, Juze Yang, Jiayi Ren, Xiaowei Mao, Jia Li, Tengfei Sun, Liangliang Dong, Enguo Chen, Yan Lu, Pengyuan Liu   +9 more
wiley   +1 more source

Case Report: Near-complete resolution of nail psoriasis with upadacitinib in a pediatric patient. [PDF]

Front Immunol
Huang Y, Wen S.
europepmc   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen, Kun Mei, Yan Yang, Mengna Xu, Xinyue Dai, Renjun Gu, Fuqiong Zhou, Cheng Wang, Meiqi Chang, Yan Huang, Yu Chen   +10 more
wiley   +1 more source

Clinical manifestations of patients with <i>STAT1</i> gain-of-function variants in Mexico. [PDF]

Front Immunol
Cova-Guzmán TL, Okada S, Tsumura M, O Farrill-Romanillos PM, Martínez-Barricarte R, Román-Montes CM, Yamazaki-Nakashimada MA, Gámez-González LB, López-Martínez V, Meléndez-Díaz GM, Zuñiga-Lagunes CG, Gómez-Tello H, Nuñez-Nuñez ME, Bayardo Gutiérrez B, Staines-Boone AT, Lugo Reyes SO, Salazar-Gálvez Y, Moctezuma-Trejo C, Alaníz-Flores AK, Gómez-Hernández N, Ortega-Cisneros M, Zárate-Hernández MDC, Bustamante-Ogando JC, Soudée C, Rosain J, Boisson-Dupuis S, Migaud M, Casanova JL, Espinosa-Rosales FJ, Cristerna Tarrasa GH, Palacios-Reyes D, Puel A, Bustamante J, Espinosa-Padilla S, Blancas Galicia L.   +34 more
europepmc   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Multisystem Langerhans cell histiocytosis with hypothyroidism and sclerosing cholangitis: a case report and review of the literature. [PDF]

J Med Case Rep
Yu J, Liu X, Yu X, Li Q, Du W.
europepmc   +1 more source

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

Advanced Science, EarlyView.
Magnetoreceptor (MagR) regulates iron homeostasis and mitochondrial function in hepatocellular carcinoma (HCC) cells. Specifically, MagR deficiency suppresses tumor cell proliferation, migration, and invasion and enhances sorafenib‐induced ferroptosis through iron accumulation.
Tao Wang, Chenghua Song, Xin He, Mengzhou Wang, Wuming Liu, Xiaolin Wang, Yuanyuan Zhang, Jia Zhang, Lin Zhang, Dan Li, Yu Zhang, Zheng Wu, Yi Lyu, Rongqian Wu   +13 more
wiley   +1 more source