Results 41 to 50 of about 54,810 (302)

Dermoscopy of the Nail Unit

open access: yes, 2021
Nail dermoscopy (onychoscopy) is being used for a more accurate diagnosis of all nail disorders and has become a routine diagnostic instrument. In daily practice, nail signs can be magnified, and dermoscopy may confirm the clinical diagnosis and guides ...
Starace M.   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Onychoscopic Evaluation of Inflammatory Nail Disorder and Their Relationship with Disease Duration: A Clinical Descriptive Study

open access: yesمجلة الكوفة الطبية
Background: Nail diseases are common problems that often exhibit diagnostic challenge for many dermatologists especially when nails are primarily affected without skin involvement.
Muhsin A. Al-Dhalimi   +1 more
doaj   +1 more source

Subungual Keratoacanthoma: A Rare Variant of Keratoacanthoma

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018
Sungungual keratoacanthoma is a rare and more aggressive variant of keratoacanthoma. The authors present a case of a 49-year-old male with a one year history of a growing exophytic nodule on the nail bed of the left first toe.
Alexandre Miroux Catarino   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Pincer nail deformity in a patient with amyotrophic lateral sclerosis

open access: yesNeurology International, 2014
Although several manifestations of skin involvement in cases of amyotrophic lateral sclerosis (ALS) have been reported, the pincer nail deformity has not been previously reported in a patient with ALS.
Youshi Fujita, Takehisa Fujita
doaj   +1 more source

Classification of Koilonychia, Beaus Lines, and Leukonychia based on Nail Image using Transfer Learning VGG-16

open access: yesJurnal Rekayasa Elektrika, 2022
Human nail disease is usually ignored since it does not reveal clinical signs that are harmful to one's health. Nail disease, on the other hand, can be an early sign of a health issue.
Sugondo Hadiyoso, Suci Aulia
doaj   +1 more source

Nails in systemic disease

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2011
Nail abnormalities secondary to systemic disease could be classified as nail abnormalities associated with systemic disease, disease of specific organ system or associated with syndromes and genodermatoses. Because nail findings are easily observable and yield valuable information, careful examination of nails could be an important diagnostic tool for ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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