Results 41 to 50 of about 56,585 (261)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Beau’s Lines and Onychomadesis: A Systematic Review of Characteristics and Aetiology
Acta Dermato-Venereologica, 2023 is missing (Short communication)
Bo Ri Kim +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Onychomadesis with lichen planus: An under-recognized manifestation
Indian Journal of Dermatology, 2015 Onychomadesis or proximal separation of the nail pate usually results from severe, generalized dermatoses like bullous diseases, hand foot and mouth disease, varicella or severe cutaneous drug reactions.
Chander Grover, Suruchi Vohra
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Jurnal Rekayasa Elektrika, 2022 Human nail disease is usually ignored since it does not reveal clinical signs that are harmful to one's health. Nail disease, on the other hand, can be an early sign of a health issue.
Sugondo Hadiyoso, Suci Aulia
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Archives of Dermatology, 1973 The second edition of The Nails in Disease is the only book available which is helpful to the practitioner in diagnosing nail disorders. The content included in this edition is richer in nail syndromes and photographs than the first edition. Evaluation of content by chapter follows. Chapter 1. Anatomy and Physiology.— Overall, Dr.
openaire +2 more sources
Subungual Keratoacanthoma: A Rare Variant of Keratoacanthoma
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018 Sungungual keratoacanthoma is a rare and more aggressive variant of keratoacanthoma. The authors present a case of a 49-year-old male with a one year history of a growing exophytic nodule on the nail bed of the left first toe.
Alexandre Miroux Catarino +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source