Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Discussion of the paper: "Rock nail reinforcement of a free surface" [PDF]
, 2011 International audienceThe paper by Papamichos and Vardoulakis represents a contribution to the mechanical modelling of a rock material reinforced by the introduction of metallic bolts or nails, with a special emphasis on the way the interactions between ...
de Buhan, Patrick, Hassen, Ghazi
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Nail psoriasis: the first experience of photodynamic curcumin therapy. [PDF]
Саратовский научно-медицинский журнал, 2017 Aim: to determine the effectiveness of the photosensitizer "Curcumin" in various concentrations (0.15%, 1%, 1.5%) in combination with visible spectrum radiation in the treatment of nail psoriasis. Material and Methods.
Utz S.R. +5 more
doaj
When all you have is a dermatoscope— start looking at the nails
Dermatology Practical & Conceptual, 2014 Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life ...
H. Haenssle +7 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Chloronychia: The goldman–fox syndrome - Implications for patients and healthcare workers
Indian Journal of Dermatology, 2020 Nail coloration has many causes and may reflect systemic disease. White nails (leukonychia) are common; rubronychia is rare, whereas green (chloronychia) is occasionally evident.
Robert A Schwartz +2 more
doaj +1 more source
Installation of insecticide-treated durable wall lining: evaluation of attachment materials and product durability under field conditions. [PDF]
, 2014 BACKGROUND: Insecticide-treated durable wall lining (DL) is a new method of vector control designed to supplement LLINs and overcome two inherent limitations of LLINs and IRS: nightly behavioural compliance and short residual activity, respectively.
Larsen, Marie Louise M +3 more
core +3 more sources
Polishing the Therapy of Onychomycosis Induced by Candida spp.: Amphotericin B–Loaded Nail Lacquer [PDF]
, 2021 Aleph M. S. Souza +10 more
openalex +1 more source