Results 71 to 80 of about 74,258 (299)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Receipt from A. Jeffrey importer of Hardware, Iron, Steel, Nails and etc

open access: yes, 1875
Receipt from A. Jeffrey importer of Hardware, Iron, Steel, Nails and etc. regarding payment received on glass panes, Nov.
A. Jeffrey Importer of Hardware, Iron, Steel, Nails and Etc
core   +1 more source

Long-term outcomes of nail bed reconstruction

open access: yesArchives of Plastic Surgery, 2019
Background There are various reconstructive options for nail bed defects. However, it is challenging not to leave a deformity. In this study, we investigated differences in outcomes depending on the reconstruction method, attempted to determine which ...
Sung Hoon Koh   +7 more
doaj   +1 more source

Nail cosmetics

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2012
The nail as an anatomic structure protects the terminal phalanx of the digit from injury. Historically, it has served as a tool for protection and for survival. As civilizations developed, it attained the additional function of adornment. Nail beautification is a big industry today, with various nail cosmetics available, ranging from nail hardeners ...
Nina A, Madnani, Kaleem J, Khan
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types

open access: yes, 2019
This study aims to investigate the comparative study of calcium phosphate coatings for flexible intramedullary nails (FINs) used to lengthen long tubular bones.
Golovkin, AS   +11 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Lateral Resistance of Nails [PDF]

open access: yes, 1953
When a piece of timber is nailed to another,the thin piece is fastened generally to the thick one. Then on nailed joints the same numbers of nails using in double shear are driven from both sides respectively. Driving all nails from one side only get the
SHIOBARA, Masasuke, 塩原, 正典
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Artificial nails and psoriasis.

open access: yes, 2005
When dealing with artificial nails, it is often mentioned that psoriasis is a contraindication because artificial nails may worsen nail psoriasis by Köbner phenomenon.(1) However, although not thoroughly discussed, other interactions between psoriasis ...
André, Josette
core   +1 more source

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