Results 81 to 90 of about 256,652 (307)

Discussion of the paper: "Rock nail reinforcement of a free surface" [PDF]

open access: yes, 2011
International audienceThe paper by Papamichos and Vardoulakis represents a contribution to the mechanical modelling of a rock material reinforced by the introduction of metallic bolts or nails, with a special emphasis on the way the interactions between ...
de Buhan, Patrick, Hassen, Ghazi
core   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Involvement of Nail Apparatus in Pemphigus Vulgaris in Ethnic Poles Is Infrequent

open access: yesFrontiers in Medicine, 2018
Pemphigus vulgaris lesions have a tendency to localize around natural body orifices. The aim here was to analyze the involvement of nail apparatus in pemphigus vulgaris.
Pawel Pietkiewicz   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Partial removal of nail matrix in the treatment of ingrowing toe nail

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objectives: Ingrowing toe nail is a frequent disorder of the foot. In this study, we evaluated the results of surgical treatment of ingrowing toe nail.\r\nMethods: Sixty-two patients (31 males, 31 females; mean age 38 years; range 11 to 72 years) with ...
Nuri Aydin   +2 more
doaj  

The effect of visual stimuli on the horribleness of awful sounds. [PDF]

open access: yes, 2007
A mass web-based experiment has been carried out to explore people’s perception of horrible sounds. The advantage of a web-based methodology is that it enables hundreds of thousands of judgements to be obtained over a diverse population.
Cox, TJ
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Establishment of Child Health Cadre as Prevention for Foodborne Disease at Primary Schools [PDF]

open access: yes, 2017
Personal health, including health on school-age children comes from food intake. But often, these foods can cause health problems, such as foodborne diseases.
Hargono, A. (Arief)   +2 more
core   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The metal finds and their implications [PDF]

open access: yes, 2012
Major interdisciplinary study of metal artefacts from major Norse site in ...
Barrett, J.H.   +3 more
core  

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