Results 81 to 90 of about 255,300 (308)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Test Excavations at the Spanish Governor\u27s Palace, San Antonio, Texas [PDF]
, 1997 Test excavations were carried out in October 1996 by the Center for Archaeological Research of The University of Texas at San Antonio in front of the Spanish Governor\u27s Palace in Military Plaza in downtown San Antonio.
Fox, Anne A.
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Common surgery, uncommon complication
Dermatology Practical & Conceptual, 2015 Ingrown nail surgery is the one of the most common surgeries in outpatient clinics that are generally perfomed in response to patient complaints. Still, making simple observations, taking patient histories and conducting further tests are often neglected
Hande Akdeniz +3 more
doaj +1 more source
An approach to hygiene education among rural Indian school going children [PDF]
, 2008 Objectives: To find out the prevalence of intestinal parasites and its epidemiological correlates among rural Indian school going (6-14 years) children and to study the effect of focused, need based child to child hygiene education on personal hygiene of
Boratne, AV +4 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The metal finds and their implications [PDF]
, 2012 Major interdisciplinary study of metal artefacts from major Norse site in ...
Barrett, J.H. +3 more
core
, 2014 Objective: The authors present the first clinical results in treatment of calcaneal fractures using a newly developed calcaneal nail (C-NAIL). In their presentation the authors describe the clinical study, the indication for the minimal-invasive operation and explain in detail the surgical procedure[for full text, please go to the a.m. URL]
Pompach, M +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Partial removal of nail matrix in the treatment of ingrowing toe nail
Acta Orthopaedica et Traumatologica Turcica, 2020 Objectives: Ingrowing toe nail is a frequent disorder of the foot. In this study, we evaluated the results of surgical treatment of ingrowing toe nail.\r\nMethods: Sixty-two patients (31 males, 31 females; mean age 38 years; range 11 to 72 years) with ...
Nuri Aydin +2 more
doaj