Results 1 to 10 of about 1,570 (124)

Prevalence and Associated Factors of Diabetes Mellitus Type 2 Among Tuberculosis Patients in Muscat, Oman, 2017–2020 [PDF]

Oman Medical Journal, 2023
Objectives: Diabetes mellitus (DM) and tuberculosis (TB) are global public health concerns and leading causes of mortality and morbidity worldwide. Coinfection is known to complicate TB control and outcomes.
Sumaiya Al Amri, Jeffery Singh, Lamya Al Balushi, Thamra Al Ghafri, Mahim Nasser Al Balushi, Hanan Al Marbouai, Khalid Salim Al Dhuhli, Khalid Khalfan Al Nairi, Moza Suliman Al Badi, Sami Mohammad Al Mujaini, Eman Elsayed Abd-Ellatif   +10 more
doaj   +2 more sources

Novel Design of Co-Poly(Hydrazide Imide) and Its Complex with Cu(I) for Membrane Separation of Methanol/Dimethyl Carbonate Mixture [PDF]

Membranes, 2023
Poly(2,2′-biquinoline-6,6′-dicarbohydrazide)-co-(bistrimelliteimide)methylene-bisanthranylide (PHI) and its metal–polymer complex PHI-Cu(I) containing several types of functional groups (hydrazide, carboxyl, amide, and imide fragments) were synthesized ...
Galina Polotskaya, Nadezhda Tian, Ilya Faykov, Mikhail Goikhman, Irina Podeshvo, Nairi Loretsyan, Iosif Gofman, Konstantin Zolotovsky, Alexandra Pulyalina   +8 more
doaj   +2 more sources

Primary retroperitoneal nodal endometrioid carcinoma associated with Lynch syndrome: A case report [PDF]

Frontiers in Oncology, 2023
We report a rare case of primary nodal, poorly differentiated endometrioid carcinoma associated with Lynch syndrome. A 29-year-old female patient was referred by her general gynecologist for further imaging with suspected right-sided ovarian endometrioid
Daniela Fischerova, Umberto Scovazzi, Natacha Sousa, Tatevik Hovhannisyan, Andrea Burgetova, Pavel Dundr, Kristýna Němejcová, Rosalie Bennett, Michal Vočka, Filip Frühauf, Roman Kocian, Tereza Indrielle-Kelly, David Cibula   +12 more
doaj   +2 more sources

Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C [PDF]

Nature Communications, 2022
The authors used novel single-molecule technology to measure the affinity of interactions between the ubiquitin ligase APC/C and its substrates, providing insights into the control of APC/C substrate destruction during mitosis.
Nairi Hartooni, Jongmin Sung, Ankur Jain, David O. Morgan   +3 more
doaj   +2 more sources

Fatal Case of Viral Pneumonia Associated with Metapneumovirus Infection in a Patient with a Burdened Medical History [PDF]

Microorganisms
Background: Human metapneumovirus (hMPV) is a respiratory pathogen that causes illness ranging from mild upper respiratory tract infections to severe pneumonia, particularly in individuals with comorbidities.
Parandzem Khachatryan, Naira Karalyan, Hasmik Petunts, Sona Hakobyan, Hranush Avagyan, Zarine Ter-Pogossyan, Zaven Karalyan   +6 more
doaj   +2 more sources

A Screen for Small Molecules to Target Candida albicans Biofilms [PDF]

Journal of Fungi, 2020
The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molecules and
Matthew B. Lohse, Craig L. Ennis, Nairi Hartooni, Alexander D. Johnson, Clarissa J. Nobile   +4 more
doaj   +2 more sources

Emerging models and trends in mental health crisis care in England: a national investigation of crisis care systems [PDF]

BMC Health Services Research, 2021
Background Inpatient psychiatric care is unpopular and expensive, and development and evaluation of alternatives is a long-standing policy and research priority around the world.
Christian Dalton-Locke, Sonia Johnson, Jasmine Harju-Seppänen, Natasha Lyons, Luke Sheridan Rains, Ruth Stuart, Amelia Campbell, Jeremy Clark, Aisling Clifford, Laura Courtney, Ceri Dare, Kelly Kathleen, Chris Lynch, Paul McCrone, Shilpa Nairi, Karen Newbigging, Patrick Nyikavaranda, David Osborn, Karen Persaud, Martin Stefan, Brynmor Lloyd-Evans   +20 more
doaj   +2 more sources

Clinical outcome and biomarker assessments of a multi-centre phase II trial assessing niraparib with or without dostarlimab in recurrent endometrial carcinoma [PDF]

Nature Communications, 2023
Treatment options in patients with recurrent endometrial carcinoma (EC) are limited and response rates to chemotherapy are poor. Here the authors report the results of a phase II trial of niraparib (PARP inhibitor) monotherapy or in combination with ...
Ainhoa Madariaga, Swati Garg, Nairi Tchrakian, Neesha C. Dhani, Waldo Jimenez, Stephen Welch, Helen MacKay, Josee-Lyne Ethier, Lucy Gilbert, Xuan Li, Angela Rodriguez, Lucy Chan, Valerie Bowering, Blaise Clarke, Tong Zhang, Ian King, Gregory Downs, Tracy Stockley, Lisa Wang, Smitha Udagani, Amit M. Oza, Stephanie Lheureux   +21 more
doaj   +2 more sources

Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study [PDF]

RMD Open, 2023
Objectives In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients.Methods We conducted a retrospective multicentre study in referral centres ...
Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo   +56 more
doaj   +2 more sources

Genewise detection of variants in MEFV gene using nanopore sequencing [PDF]

Frontiers in Genetics
Familial Mediterranean Fever (FMF) is a genetic disorder with complex inheritance patterns and genotype-phenotype associations, and it is highly prevalent in Armenia. FMF typically follows an autosomal recessive inheritance pattern (OMIM: 249100), though
Lilit Ghukasyan, Gisane Khachatryan, Gisane Khachatryan, Tamara Sirunyan, Tamara Sirunyan, Arpine Minasyan, Siras Hakobyan, Siras Hakobyan, Andranik Chavushyan, Varduhi Hayrapetyan, Varduhi Hayrapetyan, Hovsep Ghazaryan, Gevorg Martirosyan, Gohar Mkrtchyan, Valentina Vardanyan, Valentina Vardanyan, Vahan Mukuchyan, Ashot Davidyants, Roksana Zakharyan, Roksana Zakharyan, Arsen Arakelyan, Arsen Arakelyan, Arsen Arakelyan   +22 more
doaj   +2 more sources