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A Minigenome Study of Hazara Nairovirus Genomic Promoters [PDF]
A minigenome system for HAZV, closely related to CCHFV, was used to study its genome replication. HAZV genome ends, like those of other sNSV, such as peribunyaviruses and arenaviruses, are highly complementary and serve as promoters for genome synthesis.
Yusuke Matsumoto +2 more
exaly +4 more sources
Grotenhout Virus, a Novel Nairovirus Found in Ixodes ricinus in Belgium [PDF]
ABSTRACT We report here the draft genome of a novel nairovirus, Grotenhout virus, isolated from deer ticks ( Ixodes ricinus ) in Belgium. The genome consists of two segments, L and S, and is most similar to the tick-borne South Bay virus, with amino acid identities ranging from 60 to 64%.
Bert Vanmechelen +2 more
exaly +3 more sources
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Inhibition of Dugbe nairovirus replication by human MxA protein
Virus Research, 2004Sensitivity to the interferon-induced protein, MxA, has previously been demonstrated for viruses belonging to the Orthobunyavirus, Hantavirus and Phlebovirus genera of the Bunyaviridae family. We have extended these findings to a member of the fourth and remaining genus containing viruses that infect man and other animals, the nairovirus Dugbe virus ...
Friedemann Weber
exaly +4 more sources
Polypeptide Synthesis of Dugbe Virus, a Member of the Nairovirus Genus of the Bunyaviridae
The replication of Dugbe (DUG) virus, a member of the Nairovirus genus of the Bunyaviridae, has been investigated. During the infection of BS-C-1 cells a virus-specific c.p.e. was initially observed followed by recovery of the cell monolayer but with continued production of infectious virus.
exaly +3 more sources
The Proteins and RNAs Specified by Clo Mor Virus, a Scottish Nairovirus
The proteins and RNAs of Clo Mor virus have been analysed. Virus-specific proteins in infected cells had previously been identified by isotopic labelling and radioimmunoprecipitation; these were three glycoproteins (mol. wt. 115K, 90K and 80K) and an unglycosylated nucleocapsid (N) protein (50K).
G E, Watret, R M, Elliott
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Dugbe Nairovirus S Segment: Correction of Published Sequence and Comparison of Five Isolates
The sequence of the S (small) RNA segment of the ArD 44313 isolate of Dugbe nairovirus (DUG) has been redetermined, and a number of apparent errors in the previously reported sequence (V. K. Ward, A. C. Marriott, A. A. El-Ghorr, and P. A. Nuttall, 1990, Virology 175, 518-524) were revealed.
Bridgen, Anne +2 more
exaly +3 more sources
The Nairoviridae family within the Bunyavirales order comprise tick-borne segmented negative-sense RNA viruses that cause serious disease in a broad range of mammals, yet cause a latent and lifelong infection in tick hosts. An important member of this family is Crimean-Congo haemorrhagic fever virus (CCHFV), which is responsible for serious human ...
Lesley Bell-Sakyi +2 more
exaly +4 more sources
Dugbe nairovirus M RNA: Nucleotide sequence and coding strategy
Virology, 1992The coding assignments of the medium-sized (M) RNA segment of the Dugbe (DUG) virus (Nairovirus, Bunyaviridae) were investigated. The complete nucleotide sequence of 4888 nucleotides (nt) contained one long open reading frame in the viral complementary RNA, extending from an AUG start codon at nt 48-50 to a stop codon at nt 4701-4703 (numbered from the
A C, Marriott +2 more
openaire +2 more sources
The genus Nairovirus (family Bunyaviridae) contains seven serogroups consisting of 34 predominantly tick-borne viruses, including several associated with severe human and livestock diseases [e.g., Crimean Congo hemorrhagic fever (CCHF) and Nairobi sheep disease (NSD), respectively].
Honig, Jessica E. +2 more
exaly +3 more sources
Non-viral sequences at the 5' ends of Dugbe nairovirus S mRNAs
Analyses of the mRNA transcription processes of viruses in four genera (Bunyavirus, Hantavirus, Phlebovirus and Tospovirus) of the family Bunyaviridae have revealed a common mechanism of initiation using host-derived primers, known as cap-snatching. To provide similar information on the fifth genus in the family, the 5' ends of Dugbe nairovirus S mRNA ...
H, Jin, R M, Elliott
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