Results 81 to 90 of about 1,757 (150)

Development of Molecular Host-Centric Methodology Seeking to Pinpoint Reservoirs of Nairoviruses by Interferon-Stimulated Gene Product 15 [PDF]

, 2023
Nairoviruses, tick-borne viruses from the Bunyaviridae family, pose persistent and significant threats to human health. While the most notable is Crimean-Congo hemorrhagic fever virus (CCHFV), which possesses a fatality rate pushing 30%, other ...
Jalf, Amrit Singh
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Crimean-Congo Hemorrhagic Fever Virus IgG in Goats, Bhutan

Emerging Infectious Diseases, 2016
Sonam Wangchuk, Sonam Pelden, Tenzin Dorji, Sangay Tenzin, Binay Thapa, Sangay Zangmo, Ratna Gurung, Kinzang Dukpa, Tenzin Tenzin   +8 more
doaj   +1 more source

Evaluation of two inoculation routes of an adenovirus-mediated viral protein inhibitor in a Crimean-Congo hemorrhagic fever mouse model

Virus Research
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus with a wide geographic spread that can cause severe and lethal disease. No specific medical countermeasures are approved to combat this illness.
Florine E.M. Scholte, Jessica R. Spengler, Stephen R. Welch, Jessica R. Harmon, JoAnn D. Coleman-McCray, Katherine A. Davies, Scott D. Pegan, Joel M. Montgomery, Christina F. Spiropoulou, Éric Bergeron   +9 more
doaj   +1 more source

Optimization of a non-radioactive assay for monitoring endogenous reverse transcriptase activity in nairovirus-infected tick cells

reservedLa Febbre Emorragica della Crimea e del Congo (CCHF) è una malattia virale trasmessa da zecche causata dal CCHFV. Il CCHFV può infettare persistentemente le zecche, che rappresentano il serbatoio e principale vettore di trasmissione del virus.
STEFANI, ROBERTA
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Selectivity pocket of nairovirus vOTUs.

, 2019
(A) The CCHFV vOTU Ub bound structure (PDB ID 3PRP) is shown with the location of the selectivity pocket indicated with a box. The selectivity pockets of the other vOTUs are shown, with the Ub (purple) modeled in from the CCHFV structure based on a ...
John V. Dzimianski (6195842), Scott D. Pegan (832047), Courtney M. Daczkowski (5374682), Florine E. M. Scholte (440416), Octavia Y. Goodwin (739701), Éric Bergeron (5663428), Brianna S. Beldon (6195845)   +6 more
core   +1 more source

Characterization of Nairovirus replication in Hyalomma-derived tick cell lines

, 2014
Background: Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic viral disease that is asymptomatic in infected animals, but a serious threat to humans.
Helen Karlberg, SALATA, CRISTIANO, Ali Mirazimi, Lesley Bell Sakyi   +3 more
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Assessment of Recombination in the S-segment Genome of Crimean-Congo Hemorrhagic Fever Virus in Iran

Journal of Arthropod-Borne Diseases, 2016
Background: Crimean-Congo Hemorrhagic Fever Virus (CCHFV) belongs to genus Nairovirus and family Bunyaviridae. The main aim of this study was to investigate the extent of recombination in S-segment genome of CCHFV in Iran. Methods: Samples were isolated
Sadegh Chinikar, Nariman Shah-Hosseini, Saeid Bouzari, MohammadAli Shokrgozar, Ehsan Mostafavi, Tahmineh Jalali, Sahar Khakifirouz, Martin H Groschup, Matthias Niedrig   +8 more
doaj  

Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever

Journal of Arthropod-Borne Diseases, 2017
Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus.
Fazilet Duygu, Tugba Sari, Turan Kaya, Nermin Bulut   +3 more
doaj  

Meta-transcriptomic profiling of Ixodes ricinus and Ixodes persulcatus ticks from Finland reveals diverse RNA viromes, community structuring, and emerging viral lineages. [PDF]

Arch Virol
Alale TY, Mänttäri J, Viitaniemi HM, Ozerov M, Baltazar-Soares M, Sormunen JJ, Vesterinen EJ.   +6 more
europepmc   +1 more source

PLoS One [PDF]

Tick-borne nairoviruses (order Bunyavirales) encode an ovarian tumor domain protease (OTU) that suppresses the innate immune response by reversing the post-translational modification of proteins by ubiquitin (Ub) and interferon-stimulated gene product 15

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