Results 131 to 140 of about 96,262 (339)
Take-home naloxone and the politics of care.
Sociology of Health and Illness, 2019 'Take-home naloxone' refers to a life-saving intervention in which a drug (naloxone) is made available to nonmedically trained people for administration to other people experiencing an opioid overdose.
A. Farrugia +6 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño +9 more
wiley +1 more source
Paraventricular Nucleus Modulates Excitatory Cardiovascular Reflexes during Electroacupuncture. [PDF]
, 2016 The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN.
Fu, Liang-Wu +3 more
core +1 more source
Targeting RNA Polymerase I in Ewing Sarcoma Treatment
Cancer Science, EarlyView.Pharmacologic inhibition of RNA polymerase I activity represents a new therapeutic approach for Ewing sarcoma. This is the first time key components of the ribosome biogenesis pathway have been linked to Ewing sarcoma biology.
Alexis Bruce +7 more
wiley +1 more source
Modifications of Gait as Predictors of Natural Osteoarthritis Progression in STR/Ort Mice [PDF]
, 2014 OBJECTIVE: Osteoarthritis (OA) is a common chronic disease for which disease-modifying therapies are not currently available. Studies to seek new targets for slowing the progress of OA rely on mouse models, but these do not allow for longitudinal ...
Bevan, S +10 more
core +4 more sources
Buprenorphine/naloxone – one formulation that doesn’t fit all: a case report
Harm Reduction JournalBackground Sublingual buprenorphine, approved for treatment of opioid use disorder since 2002, is most commonly available in co-formulation with naloxone.
Hannan M. Braun +2 more
doaj +1 more source
Innovative Drug Delivery and Formulation Designs To Deter Drug Abuse/Misuse Related To Suicide [PDF]
, 2012 Patients with a history of abuse/misuse of pain and psychotic medications are at high risk for suicide. Novel drug delivery and formulation approaches have been explored to reduce the potential of drug abuse/misuse and to improve patient compliance. This
Zhao, Fang
core +1 more source
Harm reduction among injecting drug users - evidence of effectiveness [PDF]
, 2010 This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Goldberg, David +5 more
core +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have emerged as key agents for weight management, based on their marked efficacy as observed in randomized controlled trials. While still limited, real‐world studies on GLP‐1RA use in populations with obesity are increasingly available. This narrative review discusses contemporary real‐world
Reimar W. Thomsen +3 more
wiley +1 more source
Effects of single injection of naloxone and damgo within nucleus accumbens septi in the plus maze test in rats [PDF]
, 2018 Nucleus accumbens septi (NAS) is studied because its relations with cognition and anxiety. Its pharmacological manipulation is widely used in experimental psychopathology to reproduce psychotic signs and symptoms in animal models.
Baiardi, Gustavo Carlos +10 more
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