Results 291 to 300 of about 96,262 (339)
Some of the next articles are maybe not open access.
Prehospital Emergency Care, 2021
Objective: U.S. opioid overdoses increased nearly sixfold from 1999 to 2018, and greater than 1% of all emergency medical services (EMS) encounters now involve naloxone administration. While “treat and release” protocols may have low short-term mortality,
A. Zozula +4 more
semanticscholar +1 more source
Objective: U.S. opioid overdoses increased nearly sixfold from 1999 to 2018, and greater than 1% of all emergency medical services (EMS) encounters now involve naloxone administration. While “treat and release” protocols may have low short-term mortality,
A. Zozula +4 more
semanticscholar +1 more source
The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime
Journal law and economy, 2021The United States is experiencing an epidemic of opioid abuse. In response, states have implemented policies including increased access to naloxone, a drug that can save lives when administered during an overdose.
Jennifer L. Doleac, Anit Mukherjee
semanticscholar +1 more source
Annals of Emergency Medicine, 1983
Naloxone hydrochloride, a synthetic N-allyl derivative of oxymorphone, is an effective agent for the reversal of the cardiovascular and respiratory depression associated with narcotic and possibly some non-narcotic overdoses. It is essentially a pure narcotic antagonist, is relatively safe, and is a useful diagnostic and therapeutic agent.
K A, Handal +2 more
openaire +2 more sources
Naloxone hydrochloride, a synthetic N-allyl derivative of oxymorphone, is an effective agent for the reversal of the cardiovascular and respiratory depression associated with narcotic and possibly some non-narcotic overdoses. It is essentially a pure narcotic antagonist, is relatively safe, and is a useful diagnostic and therapeutic agent.
K A, Handal +2 more
openaire +2 more sources
Microinduction of Buprenorphine/Naloxone: A Review of the Literature.
American Journal on Addictions, 2020BACKGROUND AND OBJECTIVES Buprenorphine's high-binding affinity as a partial µ-opioid agonist displaces preexisting full agonists causing precipitated withdrawal, which requires most individuals starting buprenorphine to endure moderate withdrawal prior ...
Saeed Ahmed +3 more
semanticscholar +1 more source
Cochrane Database of Systematic Reviews, 2003
There is pre-clinical evidence, involving several animal species, suggesting that opioid peptides play a role in the physiopathology of shock (endotoxic, hypovolemic, cardiogenic, spinal, anaphylactic). Many case reports have suggested that naloxone (an opiate antagonist) might be an effective treatment for shock in humans, but others have not ...
B, Boeuf +6 more
openaire +3 more sources
There is pre-clinical evidence, involving several animal species, suggesting that opioid peptides play a role in the physiopathology of shock (endotoxic, hypovolemic, cardiogenic, spinal, anaphylactic). Many case reports have suggested that naloxone (an opiate antagonist) might be an effective treatment for shock in humans, but others have not ...
B, Boeuf +6 more
openaire +3 more sources
Naloxone and Alcoholic Intoxication
Annals of Internal Medicine, 1982Excerpt To the editor: In a recent article, Lyon and Antony (1) reported the dramatic effect of naloxone hydrochloride in two comatose patients with alcoholic intoxication.
Lignian, Hervé +2 more
openaire +3 more sources
Perinatal naloxone: When does naloxone affect hyperalgesia?
Pharmacology Biochemistry and Behavior, 1979Pregnant mice were treated with naloxone via subcutaneous implants, from about 5 days prior to parturition. At birth entire litters were cross-fostered so that groups of offspring were exposed to naloxone treated mothers; before birth, after birth to weaning, from about 5 days prior to birth to weaning, or not exposed to naloxone.
Harvey Monder +2 more
openaire +3 more sources
American Journal on Addictions, 2019
BACKGROUND AND OBJECTIVES Buprenorphine/naloxone has been shown to be effective in the treatment of opioid use disorder. Due to its pharmacological properties, induction can be challenging, time-consuming, and result in sudden onset of withdrawal ...
Sukhpreet Klaire +5 more
semanticscholar +1 more source
BACKGROUND AND OBJECTIVES Buprenorphine/naloxone has been shown to be effective in the treatment of opioid use disorder. Due to its pharmacological properties, induction can be challenging, time-consuming, and result in sudden onset of withdrawal ...
Sukhpreet Klaire +5 more
semanticscholar +1 more source
Naloxone in Hepatic Encephalopathy
Archives of Pediatrics & Adolescent Medicine, 1985Sir .—The prognosis of hepatic encephalopathy in general is extremely guarded. By using levodopa (100 mg/kg), 23 of 39 patients with hepatic encephalopathy related to different liver diseases responded to treatment, and 17 of them were discharged in an uncontrolled study.
Şinasi Özsoylu, Nurten Koçak
openaire +3 more sources
Intranasal Naloxone Administration
New England Journal of Medicine, 2021Intranasal Administration of Naloxone Intranasal naloxone is used to treat patients with respiratory and central nervous system depression that is known or suspected to be caused by an opioid overd...
Rafael Ortega +4 more
openaire +3 more sources