Results 151 to 160 of about 48,575 (332)

Halymenia durvillei Extracts Exert Antiobesity Effects by Targeting hosl‐1‐Mediated Lipolysis in a Glucose‐Induced Caenorhabditis elegans Model

eFood, Volume 6, Issue 3, June 2025.
This study demonstrates the antiobesity potential of Halymenia durvillei (H. durvillei) extracts using a Caenorhabditis elegans (C. elegans) obesity model. The extracts significantly reduced total fat accumulation, lowered reactive oxygen species (ROS) levels, and extended the lifespan in glucose‐fed C. elegans. These beneficial effects may be mediated
Kawita Chumphoochai, Sukrit Promtang, Pawanrat Chalorak, Preeyanuch Manohong, Nakorn Niamnont, Montakan Tamtin, Prasert Sobhon, Simon Tuck, Krai Meemon   +8 more
wiley   +1 more source

Efficacy and Tolerability of Long-Acting Injectable Naltrexone for Alcohol Dependence: A Randomized Controlled Trial

Gynecologic Oncology, 2005
M. Güngör, F. Ortaç, M. Arvas, Derin Kösebay, Murat Sönmezer, Kenan Köse   +5 more
semanticscholar   +1 more source

Bioabsorbable, subcutaneous naltrexone implants mitigate fentanyl‐induced respiratory depression at 3 months—A pilot study in male canines

Physiological Reports
The aim of this study is to determine if extended‐release, bioabsorbable, subcutaneous naltrexone (NTX) implants can mitigate respiratory depression after an intravenous injection (IV) of fentanyl. Six different BIOabsorbable Polymeric Implant Naltrexone
Robert L. Joyner, Joseph A. Hollenbaugh, Donald D'Aquila, Marc Fishman, Steven M. Cohen, Veera Holdai, Jeffrey D. Benner   +6 more
doaj   +1 more source

Use of pharmacological treatments by a sample of Italian patients affected by alcohol use disorders [PDF]

, 2012
Title: USE OF PHARMACOLOGICAL TREATMENTS BY A SAMPLE OF ITALIAN PATIENTS AFFECTED BY ALCOHOL USE DISORDERS Author name(s): R. Agabio; E.M. Diana; D. Grazzini; R. Pirastu; G.L.
AGABIO, ROBERTA, Diana EM, Grazzini D, Pirastu R, Gessa GL   +4 more
core  

Efficacy of naloxone in reducing hypoxemia and duration of immobility following focal to bilateral tonic–clonic seizures

Epilepsia Open, Volume 10, Issue 3, Page 880-893, June 2025.
Abstract Objective Evaluating the efficacy of an opioid antagonist, naloxone (NLX), to reduce the severity of post‐ictal hypoxemia and immobility after focal to bilateral tonic–clonic seizures (FBTCS). Methods ENALEPSY is a double‐blind placebo (PCB)‐controlled trial conducted in patients with focal epilepsy undergoing long‐term video‐EEG monitoring ...
Sylvain Rheims, Fatima Chorfa, Véronique Michel, Edouard Hirsch, Louis Maillard, Luc Valton, Fabrice Bartolomei, Philippe Derambure, Vincent Navarro, Julien Biberon, Arielle Crespel, Anca Nica, Martine Lemesle Martin, Laure Mazzola, Jerome Petit, Vincent Rossero, Sébastien Boulogne, Mathilde Leclercq, Laurent Bezin, Catherine Mercier, Pascal Roy, Philippe Ryvlin, on behalf of the ENALEPSY Study Group, V. Michel, M. De Montaudouin, M. Lemesle Martin, P. Kahane, L. Minotti, L. Vercueil, A. S. Jobst, J. Petit, D. Tourniaire, V. Eid, P. Latour, P. Derambure, W. Szurhaj, S. Rheims, H. Catenoix, N. Andre‐Obadia, J. Isnard, A. Montavont, S. Boulogne, F. Bartolomei, A. Trébuchon, A. Mc Gonigal, S. Aubert, S. Lagarde, A. Crespel, P. Gelisse, B. Mercedes, L. Maillard, L. Tyvaert, J. P. Vignal, V. Navarro, S. Dupont, C. Adam, V. Frazzini, V.‐H. Nguyen‐Michel, M. Damiano, V. Lambrecq, A. Biraben, A. Nica, P. Convers, L. Mazzola, E. Hirsch, M. P. Valenti, J. Scholly, C. Behr, L. Valton, M. Denuelle, J. Curot, J. Biberon   +71 more
wiley   +1 more source

Naltrexone Alters Subjective and Psychomotor Responses to Alcohol in Heavy Drinking Subjects [PDF]

, 2000
Mary E. McCaul, Gary S. Wand, Thomas Eissenberg, Charles A. Rohde, Lawrence J. Cheskin   +4 more
openalex   +1 more source

Research progress on the mechanisms of pain empathy

Ibrain, Volume 11, Issue 2, Page 146-161, Summer 2025.
This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu, Siwei Wang, Yan Yan, Bangyong Qin, Qingxiang Mao, Jie Yuan   +5 more
wiley   +1 more source

Florid opioid withdrawal–like reaction precipitated by naltrexone in a patient with chronic cholestasis [PDF]

, 2000
E. Anthony Jones, Henk L. Dekker
openalex   +1 more source

Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats. [PDF]

, 2019
Prescription opioids, such as oxycodone, are highly effective analgesics for clinical pain management, but approximately 25% of patients who are prescribed opioids misuse them, and 5%-10% develop an opioid use disorder (OUD).
de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Newman, Amy H, Sedighim, Sharona   +4 more
core  

Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria

International Journal of Methods in Psychiatric Research, Volume 34, Issue 2, June 2025.
ABSTRACT Aim The heterogeneous metrics and criteria used to assess the effectiveness of substance use disorders treatment hinders cross‐study comparisons. This review aims to parse such heterogeneity by analysing the operational definitions of variables used to derive metrics and outcome criteria, contributing to the standardisation process. Methods We
Marta Narváez‐Camargo, Oscar Lozano‐Rojas, Cinta Mancheño‐Velasco, Antonio Verdejo‐García   +3 more
wiley   +1 more source