Results 311 to 320 of about 48,575 (332)
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Analysis of naltrexone urinary metabolites
Journal of Pharmaceutical and Biomedical Analysis, 1988A reversed-phase HPLC method using ion-pair formation has been developed for the simultaneous determination of naltrexone and three urinary metabolites. The extraction of the free and conjugated metabolites was studied by liquid-solid procedures using styrene-divinylbenzene copolymers (Amberlite XAD-2) and bonded octadecyl silica supports (ODS-silica).
Jordi Segura +2 more
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2019
Naloxone is a highly specific, high-affinity opioid antagonist used to reverse the effects of opioids. It is available in several formulations for convenient administration by medical trained personnel and by lay persons in the ambulatory setting. Naltrexone is available orally or by long acting intramuscular injection for alcohol or opioid dependence ...
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Naloxone is a highly specific, high-affinity opioid antagonist used to reverse the effects of opioids. It is available in several formulations for convenient administration by medical trained personnel and by lay persons in the ambulatory setting. Naltrexone is available orally or by long acting intramuscular injection for alcohol or opioid dependence ...
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Naltrexone-3-salicylate (a prodrug of naltrexone): synthesis and pharmacokinetics in dogs.
Pharmaceutical research, 1988Naltrexone-3-salicylate (3), a prodrug of naltrexone (1), was prepared by a simple procedure from naltrexone-3-acetylsalicylate (2). The plasma (dog and human) hydrolysis half-life of 3 was found to be approximately 30 min. Compound 2 was previously shown to hydrolyze in dog and human plasma with a fast deacetylation step to 3, followed by slower ...
Munir A. Hussain, Eli Shefter
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Nontolerance to the opioid antagonism of naltrexone
Biological Psychiatry, 1985Controlled opiate challenges of naltrexone-pretreated human subjects have established that naltrexone is an effective opioid antagonist. However, these challenges have been conducted after relatively acute dosing with naltrexone, and tolerance to this antagonism after chronic treatment is possible.
Mark Topazian +3 more
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Low-Dose Naltrexone for Chronic Pain: Update and Systemic Review
Current Pain and Headache Reports, 2020P. S. Kim, Michael A. Fishman
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Experiences with Naltrexone in Buffalo
The American Journal of Drug and Alcohol Abuse, 1975Zebulon Taintor +5 more
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Occupancy of the kappa opioid receptor by naltrexone predicts reduction in drinking and craving
Molecular Psychiatry, 2020B. de Laat +6 more
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Naltrexone for Alcohol Dependence
New England Journal of Medicine, 2002Gabriel Rubio +2 more
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