Results 21 to 30 of about 59,458 (179)

A Randomized, Blinded, Placebo-Controlled Crossover Study of the Pharmacokinetics and Pharmacodynamics of Naloxone, Naltrexone, and Nalmefene in Methadone-Sedated Working Dogs. [PDF]

open access: yesJ Vet Pharmacol Ther
ABSTRACT A randomized, blinded, placebo‐controlled crossover study was performed with eight professional working dogs to evaluate the pharmacokinetics and pharmacodynamics of three opioid reversal agents. Following sedation with 1 mg kg−1 methadone HCl IV, dogs were randomly assigned to receive naloxone, naltrexone, or nalmefene at 0.1 mg kg−1 IM, or ...
Mills T   +8 more
europepmc   +2 more sources

Comparative Safety of Glucagon-Like Peptide 1 Receptor Agonists (GLP-1-RAs) in Type 2 Diabetes and Chronic Weight Management: A Real-World Data Study. [PDF]

open access: yesPharmacoepidemiol Drug Saf
ABSTRACT Purpose This study assessed serious clinical outcomes comparing glucagon‐like peptide 1 receptor agonists (GLP‐1‐RAs) with sodium glucose co‐transporter 2 inhibitors (SGLT2‐Is) in patients with type 2 diabetes (T2DM) and patients without diabetes using two chronic weight management (CWM) regimens.
Hurwitz SR   +8 more
europepmc   +2 more sources

Morphine Sulfate and Naltrexone Hydrochloride Extended-Release Capsules: Naltrexone Release, Pharmacodynamics, and Tolerability

open access: yesPain Physician, 2011
Background: Morphine sulfate and naltrexone hydrochloride extended-release capsules (EMBEDA, King Pharmaceuticals, Inc., Bristol, TN), indicated for management of chronic, moderate-to-severe pain, contain pellets of extended-release morphine sulfate with a sequestered naltrexone core (MS-sNT).
Franklin, Johnson, Beatrice, Setnik
  +8 more sources

Cirrhosis-induced morphological changes in the retina:possible role of endogenous opioid [PDF]

open access: yesInternational Journal of Ophthalmology, 2015
AIM:To investigate the impact of cirrhosis on retinal morphology and to evaluate the role of endogenous opioids as a mediator in cirrhosis induced retinal change.METHODS:Thirty-six male rats were divided into 3 main groups; the common bile duct ligated ...
Mohammad Abdullah Algazo   +6 more
doaj   +1 more source

Enablers and hindrances for longer-term abstinence in opioid dependent individuals receiving treatment with extended-release naltrexone: A Norwegian longitudinal recovery trial (NaltRec study)

open access: yesContemporary Clinical Trials Communications, 2021
Opioid-dependence is a comprehensive, relapsing disorder with negative individual, - family, - and societal consequences. Recovery is difficult to achieve.
B.M. Weimand   +3 more
doaj   +1 more source

Design and Construction of a Naltrexone Selective Sensor Based on Computational Study for Application in Pharmaceutical Analysis

open access: yesInternational Journal of Electrochemical Science, 2009
Naltrexone is an opioid antagonist, which has been used for treatment of alcoholism and opiate dependence. In this study, the electronic and geometric properties of Naltrexone, sodium tetraphenyl borate and their complexes were studied by computational ...
Mohammad Reza Ganjali   +3 more
doaj   +1 more source

Phytochemical composition and antinociceptive activity of Bauhinia glauca subsp. hupehana in rats. [PDF]

open access: yesPLoS ONE, 2015
In traditional medicine, Bauhinia glauca subsp. hupehana has long been used as an analgesic agent in China. The aim of this study was to evaluate the antinociceptive activity of the ethanol extract of the aerial parts of B. glauca subsp.
Jinlong Xu   +6 more
doaj   +1 more source

Opiate agonists and antagonists modulate taste perception in opiate-maintained, and recently detoxified subjects. [PDF]

open access: yes, 2013
Heroin addicts consume large quantities of refined sugars. This study investigated the effect of opiate use and antagonism on sweet taste in opiate-maintained drug users and detoxified former chronic opiate users, using a within-subject design.
Green, Amy   +14 more
core   +1 more source

Night eating syndrome (NES). A case report of NES

open access: yesEuropean Psychiatry, 2023
Introduction The night eating syndrome (NES, DSM-V: 307.59) was described in 1955 as a disorder defined by morning anorexia, nocturnal hyperphagia (25% of the daily intake of food during sleep) and insomnia. Attributed to a delay in the circadian rhythm
B. Pascual Garcia   +2 more
doaj   +1 more source

Potential Therapeutic Benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of Transient Receptor Potential Melastatin 3 Ion Channels in Pathophysiology and Treatment

open access: yesFrontiers in Immunology, 2021
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating multi-systemic chronic condition of unknown aetiology classified as an immune dysfunction syndrome and neurological disorder.
Helene Cabanas   +9 more
doaj   +1 more source

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