Results 11 to 20 of about 22,786 (211)
Purpose: The aim of this study was to report the 10-year visual outcome in eyes treated with anti-vascular endothelial growth factor (anti-VEGF) agents for neovascular age-related macular degeneration (nAMD) and to assess the impact of switching ...
Deepa Upasani, Narendra Dhingra
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Background/objectives Neovascular age-related macular degeneration (nAMD) is a common cause for visual impairment in the ageing population. An increasing number of nAMD patients causes significant health burden, although intravitreal anti-VEGF agents ...
Ida Korva-Gurung +3 more
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Implementation of accelerated molecular dynamics in NAMD [PDF]
Accelerated molecular dynamics (aMD) is an enhanced-sampling method that improves the conformational space sampling by reducing energy barriers separating different states of a system. Here we present the implementation of aMD in the parallel simulation program NAMD.
Yi, Wang +3 more
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Collective variable-based calculations in NAMD [PDF]
The computational power of parallel clusters and supercomputers, and of the macromolecular simulation softwares typically used has been rapidly increasing in the recent years. One of the consequences is the higher demand for methods to analyze the dynamics and conformational space of biomolecular complexes.
Fiorin, Giacomo +2 more
openaire +1 more source
Molecular dynamics recipes for genome research [PDF]
Molecular dynamics (MD) simulation allows one to predict the time evolution of a system of interacting particles. It is widely used in physics, chemistry and biology to address specific questions about the structural properties and dynamical mechanisms ...
Biagini, Tommaso +8 more
core +1 more source
Integrative metabolome and lipidome analyses of plasma in neovascular macular degeneration
Age-related macular degeneration (AMD) causes irreversible vision-loss among the elderly in industrial countries. Neovascular AMD (nAMD), which refers to late-stage AMD, is characterized by severe vision-threatening choroidal neovascularization (CNV ...
Tantai Zhao +4 more
doaj +1 more source
Main memory in HPC: do we need more, or could we live with less? [PDF]
An important aspect of High-Performance Computing (HPC) system design is the choice of main memory capacity. This choice becomes increasingly important now that 3D-stacked memories are entering the market.
Ayguadé Parra, Eduard +8 more
core +2 more sources
Antivasoproliferative therapy is a revolutionary trend in the treatment of neovascular age-related macular degeneration (nAMD), as it is aimed at blocking growth factors of the newly formed vessels.
R. R. Fayzrakhmanov
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Background The concentrations of cytokines in the aqueous humor from neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) may vary. The study was conducted to compare various cytokine levels in the aqueous humor
Huiying Zhou +3 more
doaj +1 more source
Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson +8 more
core +1 more source

