Results 51 to 60 of about 249,295 (264)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

How Does It Feel When People Forget Your Name or Name You Incorrectly?

Names
The present study investigated, using a questionnaire, how people feel (i.e., irritated, offended, and sad) when their own name was misprocessed (i.e., forgotten, uttered after a hesitation, mispronounced, or replaced by another person’s name) during a ...
Serge Brédart, Christel Devue, Valentine Vanootighem   +2 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The Impact of Attentional, Linguistic and Visual Features during Object Naming

Frontiers in Psychology, 2013
Object detection and identification are fundamental visual tasks and recent work suggests that it is primarily objects, rather than low-level salient regions, that attract our attention.
Alasdair Daniel Francis Clarke, Moreno I Coco, Moreno I Coco, Frank eKeller   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Naming in OHP

, 1999
Naming is a key issue in any distributed system. In particular, with the Open Hypermedia Systems Working Group's efforts towards openness and interoperability in Open Hypermedia Systems (OHS) resulting in the need for (globally) valid names for all types
Davis, Hugh C., Reich, Sigi, Millard, David E.   +2 more
core   +1 more source

Name our new train station

Linguistica Brunensia, 2019
In June 2018 a survey for the name of the new train station in Brno was announced. The article analyses name proposals which were collected by the Brno municipality. Some proposals were serious, some humorous and provocative.
Žaneta Dvořáková
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Dinî Güfte Mecmuaları Alanını İnşa Etmeye Dönük Bir Çaba : Tasnif ve İsimlendirme

Dini Araştırmalar
Bir şeyi belirli sınıflara ve takımlara ayırma, düzenleme anlamlarına gelen tasnif kavramı, terimsel manada ilimleri özelliklerine göre sıralamak demektir.
Mustafa Said Dilek
doaj   +1 more source

Language Disorders in People with Cognitive Impairment: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The progressive ageing of the population has generated significant interest in various areas, particularly Cognitive Impairment (CI). It is necessary to know the specific characteristics of people with cognitive development to establish the
Esther Moraleda Sepúlveda, Marina Alonso Sánchez, Patricia López Resa, Noelia Santos Muriel   +3 more
doaj   +1 more source