Results 71 to 80 of about 208,959 (312)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Photographs of manipulable objects are named more quickly than the same objects depicted as line-drawings: Evidence that photographs engage embodiment more than line-drawings

Frontiers in Psychology, 2014
Previous research has shown that photographs of manipulable objects (i.e. those that can be grasped for use with one hand) are named more quickly than non-manipulable objects when they have been matched for object familiarity and age of acquisition.
Joshua P. Salmon, Heath eMatheson, Patricia eMcMullen   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Interactions between visual and semantic processing during object recognition revealed by modulatory effects of age of acquisition [PDF]

, 2013
The age of acquisition (AoA) of objects and their names is a powerful determinant of processing speed in adulthood, with early-acquired objects being recognized and named faster than late-acquired objects. Previous research using fMRI (Ellis et al., 2006.
Cornelissen, Piers, Wheat, Katherine, Woods, Will, Wheat, K.L., Simpson, M.I., Barca, Laura, Simpson, Michael, Cornelissen, P.L., Woods, W., Ellis, A.W., Urooj, U., Urooj, Uzma, Ellis, Andrew W., Barca, L.   +13 more
core   +1 more source

A Note on The Bell Jar (1963)

Names, 2013
Sylvia Plath’s novel The Bell Jar, which first appeared in print fifty years ago, is a thinly veiled depiction of a particular time in the author’s life, the summer of 1953.
Susan J Behrens
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Naming Academic Libraries: Is Institutional Identity Obscuring the Generous Benefactors and Illustrious Educators of Old?

Names, 2012
Identifying the individuals after whom academic libraries are named reveals interesting patterns. An examination of the libraries at traditionally grouped schools such as Ivy League, Seven Sisters, and Big Ten as well as the authors’ home state academic ...
Alice Crosetto, Thomas A Atwood
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Arms: a decentralised naming model for object-based distributed computing systems

, 2010
Entities communicate with one another in distributed computing systems via symbolic names. Implementing such communication requires a naming scheme that dynamically maps these symbolic names to physical nodes and processes.
Li, Jia
core  

Naming fMRI-guided white matter language tract volumes influence naming decline after temporal lobe resection. [PDF]

OBJECTIVE The aim of this study was to explore the relation of language functional MRI (fMRI)-guided tractography with postsurgical naming decline in people with temporal lobe epilepsy (TLE).
Trimmel, Karin, van Graan, Louis A, Duncan, John S., Xiao, Fenglai, Koepp, Matthias J., Thompson, Pamela J, van Graan, Louis A., Vos, Sjoerd B, Vos, Sjoerd B., Duncan, John S, Caciagli, Lorenzo, Thompson, Pamela J., Koepp, Matthias J, Binding, Lawrence   +13 more
core   +1 more source