Results 31 to 40 of about 6,543 (242)

Steroid-Induced Cardiomyopathy: Insights From a Systematic Literature Review and a Case Report. [PDF]

Clin Case Rep
ABSTRACT Anabolic‐androgenic steroids (AAS) abuse is associated with severe cardiovascular risks, particularly AAS‐induced cardiomyopathy. This systematic review highlights that most cases show left ventricular dilation and reduced ejection fraction.
Alhusban Z, Alaaraj MM, Saimeh AR, Nassar W, Awad A, Ghanima K, Abouelkheir M, Hamed AM, Afsa A, Morra ME.   +9 more
europepmc   +2 more sources

Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids [PDF]

, 2010
: BACKGROUND AND OBJECTIVE: With prolonged use of anabolic androgenic steroids (AAS), occasional incidents of renal disorders have been observed. Independently, it has also been established that there are considerable inter-individual and inter-ethnic ...
Barker, James, Deshmukh, Nawed, Hussain, Iltaf, Naughton, Declan P, Petroczi, Andrea, Szekely, Andrea D   +5 more
core   +3 more sources

Effects of nandrolone decanoate on femur morphology. Experimental study

Acta Cirúrgica Brasileira, 2021
Purpose To evaluate the immediate and late effects of nandrolone on femur morphology of rats. Methods Twenty-eight animals with 20 weeks of age were divided into four groups: C28, control animals that were euthanized eight weeks after the experiment ...
Diogo Benchimol de Souza, Flavia Bittencourt Brasil, Roger Gaspar Marchon, Bruno Félix-Patrício   +3 more
doaj   +1 more source

Nandrolone decanoate-induced hypogonadism in male rats: Dose- and time-dependent effects on pituitary and testicular hormonal functions. [PDF]

Physiol Rep
Karimi S, Kazori N, Alavi SMH, Alijanpour S, Siddiqi MAA, Zeynali B.   +5 more
europepmc   +2 more sources

Use of high-dose nandrolone aggravates septic shock in a mouse model

Kaohsiung Journal of Medical Sciences, 2011
Nandrolone, an anabolic-androgenic steroid, is widely misused by athletes who wish to rapidly increase muscle mass and performance. An increasing number of reports have indicated that nandrolone may affect and modulate the immune system. This study aimed
Che Lin, Shou-Tung Chen, Su-Yu Chien, Shou-Jen Kuo, Dar-Ren Chen, 林喆, 陳守棟, 簡素玉, 郭守仁, 陳達人   +9 more
doaj   +1 more source

Effects of Nandrolone Stimulation on Testosterone Biosynthesis in Leydig Cells [PDF]

, 2016
Anabolic androgenic steroids (AAS) are among the drugs most used by athletes for improving physical performance, as well as for aesthetic purposes. A number of papers have showed the side effects of AAS in different organs and tissues.
Barone, F., BARONE, Rosario, CAPPELLO, Francesco, DI FELICE, Valentina, DI GAUDIO, Francesca, Locorotondo, N., Maglietta, F., MARINO GAMMAZZA, Antonella, PITRUZZELLA, Alessandro, Pomara, C., Salerno, M., SANGIORGI, Claudia, Sarni, A., Turillazzi, E.   +13 more
core   +1 more source

Morphometric analysis and redox state of the testicles in nandrolone decanoate and swimming treated adult male rats

Basic and Clinical Andrology, 2021
Résumé Contexte Au cours des dernières décennies, l’abus de stéroïdes androgéniques anabolisants (SAA) est devenu populaire parmi les athlètes professionnels et récréatifs. L’abus des SAA conduit à une diminution des niveaux d’hormones sexuelles, mais la
Jasmina Sretenovic, Jovana Joksimovic Jovic, Ivan Srejovic, Vladimir Zivkovic, Katarina Mihajlovic, Milica Labudovic-Borovic, Svetlana Trifunovic, Verica Milosevic, Dejan Lazic, Sergey Bolevich, Vladimir Jakovljevic, Zoran Milosavljevic   +11 more
doaj   +1 more source

Simultaneous quantitation and identification of intact Nandrolone phase II oxo-metabolites based on derivatization and inject LC-MS/(HRMS) methodology. [PDF]

Drug Test Anal
Accurate and convenient analysis of the intact phase II oxo‐metabolites of nandrolone under the provisions of WADA's TD2023IDCR was accomplished with a dilute derivatization reagent (Girard's reagent T) and inject strategy. Abstract Α sensitive and selective derivatization and inject method for the quantification of intact nandrolone phase II oxo ...
Sakellariou P, Kiousi P, Petrou M, Angelis YS.   +3 more
europepmc   +2 more sources

PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2

Frontiers in Pharmacology, 2014
Most androgenic drugs are available as esters for a prolonged depot action. However the enzymes involved in the hydrolysis of the esters have not been identified.
Emmanuel eStrahm, Anders eRane, Lena eEkström   +2 more
doaj   +1 more source

Nandrolone decanoate interferes with testosterone biosynthesis altering blood-testis barrier components [PDF]

, 2017
The aim of this study was to investigate whether nandrolone decanoate (ND) use affects testosterone production and testicular morphology in a model of trained and sedentary mice.
Barone, F., Barone, R., Cappello, F., Cipolloni, L., D'Amico, D., Di Felice, V., Di Gaudio, F., Locorotondo, N., Marino Gammazza, A., Pitruzzella, A., Pomara, C., Rapisarda, V., Rappa, F., Salerno, M., Sangiorgi, C., Sani, G., Schiavone, S., Tambo, A., Turillazzi, E.   +18 more
core   +1 more source