Results 41 to 50 of about 7,295 (239)

Use of high-dose nandrolone aggravates septic shock in a mouse model

open access: yesKaohsiung Journal of Medical Sciences, 2011
Nandrolone, an anabolic-androgenic steroid, is widely misused by athletes who wish to rapidly increase muscle mass and performance. An increasing number of reports have indicated that nandrolone may affect and modulate the immune system. This study aimed
Che Lin   +9 more
doaj   +1 more source

Nandrolone induces a stem cell-like phenotype in human hepatocarcinoma-derived cell line inhibiting mitochondrial respiratory activity

open access: yesScientific Reports, 2020
Nandrolone is a testosterone analogue with anabolic properties commonly abused worldwide, recently utilized also as therapeutic agent in chronic diseases, cancer included.
F. Agriesti   +13 more
semanticscholar   +1 more source

PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2

open access: yesFrontiers in Pharmacology, 2014
Most androgenic drugs are available as esters for a prolonged depot action. However the enzymes involved in the hydrolysis of the esters have not been identified.
Emmanuel eStrahm   +2 more
doaj   +1 more source

Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita

open access: yesInternational Journal of Molecular Sciences, 2020
Dyskeratosis congenita (DKC) is a rare inherited disease of impaired telomere maintenance that progressively leads to multi-organ failure, including the bone marrow. By enhancing telomerase activity, androgen derivatives (ADs) are a potential therapeutic
M. Vieri   +8 more
semanticscholar   +1 more source

Synthetic androgen and new psycho-active compounds (smart drugs) abuse and dependance. Neuropathological and toxicological findings, with an approach designed for the future [PDF]

open access: yes, 2015
Self-administration of high doses of synthetic androgen (SA) is widespread among young people, to enhance physical aspect and gain muscle mass. The mechanisms of SA toxicity are not yet completely understood while the adverse effects of SA are known to ...
Fineschi, V
core   +1 more source

Steroid-Induced Cardiomyopathy: Insights From a Systematic Literature Review and a Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Anabolic‐androgenic steroids (AAS) abuse is associated with severe cardiovascular risks, particularly AAS‐induced cardiomyopathy. This systematic review highlights that most cases show left ventricular dilation and reduced ejection fraction.
Alhusban Z   +9 more
europepmc   +2 more sources

MRI and image quantitation for drug assessment - Growth effects of anabolic steroids and precursors [PDF]

open access: yes, 2005
MRI and image quantitation play an expanding role in modern drug research, because MRI offers high resolution and non-invasive ability, and provides excellent soft tissue contrast.
Tang, H, Vasselli, JR, Wu, EX
core   +1 more source

Enhanced Transport of Nandrolone Decanoate Drug by Human Serum Albumin in Presence of [BMIM]PF6 and [BMIM]BF4

open access: yesActa Chimica Slovenica, 2018
The interaction of nandrolone decanoate drug dissolved in (2%) [BMIM]BF4 or [BMIM]PF6  with human serum albumin (HSA) at different temperatures in the range of 285 – 310 K was examined by fluorescence quenching.
Zeyad J. Yasseen   +2 more
doaj   +1 more source

Qualitative screening of 116 veterinary drugs in feed by liquid chromatography-high resolution mass spectrometry. Potential application to quantitative analysis [PDF]

open access: yes, 2014
Veterinarian and human pharmaceuticals may be intentionally added to animal feed to enhance animal production. Monitoring these substances is necessary for protecting the consumers. In this work, a screening method covering 116 human and veterinary drugs
Boix Sales, Clara   +5 more
core   +1 more source

Anabolic agents: Adjuncts to nutrition support [PDF]

open access: yes, 2004
Anabolic agents as adjuncts to nutrition support therapy have been used to improve malnutrition and establish anabolism. Growth hormone, insulin-like growth factor, and anabolic steroids have been studied for their potential to reverse the catabolic ...
Gervasio, Jane M.
core   +2 more sources

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