Results 201 to 210 of about 159,461 (291)

Different chromatographic techniques and recent advancements for biomedical and pharmaceutical applications. [PDF]

North Clin Istanb
Coskun O, Akbarzadeh S, Guncer B.
europepmc   +1 more source

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

Advanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr, Andreas D. Meid, Eric Mühlberg, Manuel Ben Böhmann, Julian Quehenberger, David Wurm, Mikko Gynther, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Integrated Native Mass Spectrometry Imaging of Soluble and Membrane Proteins. [PDF]

J Am Chem Soc
Hale OJ, Cooper HJ.
europepmc   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie International Edition, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +1 more source

Miniaturized-LC in the Analysis of Emerging Organic Contaminants in Food and Environmental Samples: Recent Advances and Applications. [PDF]

Molecules
Aydoğan C, Ali A, Atakay M, Salih B, El Rassi Z.   +4 more
europepmc   +1 more source

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

Angewandte Chemie International Edition, EarlyView.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just, Nils Niemann, Petra Gnau, Dennis Kock, Thomas Heimerl, Stephan Kiontke, Lars‐Oliver Essen, Alfred Batschauer, Nina Morgner   +8 more
wiley   +1 more source

Characterization and Modeling of Industrial Phosphoric Acids' Rheological Behavior: Impact of Magnesium Monoxide on Viscosity

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigates the rheological behavior of industrial phosphoric acids (H3PO4) produced at the JORF–LASFAR phosphoric plant in Morocco, with P2O5 concentrations of 18%, 29%, 42%, and 54%. Rheological measurements were performed using a rotary cylinder rheometer over a shear rate range of 1–1000 s−1.
Hamza Belbsir, Abderrahim Benzaouia, Said Kounbach, Abdelghani Laamaoui, Said Laassiri, Khalil El‐Hami, Rachid Benhida   +6 more
wiley   +1 more source

“Dead Lithium” Formation and Mitigation Strategies in Anode‐Free Li‐Metal Batteries

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
Anode‐free lithium metal batteries, though promising due to their high energy density, face challenges from dead lithium formation. “Dead lithium”, disconnected from the anode, causes capacity loss, increased resistance, and safety risks. This review explores the origins of dead lithium, its impact on battery performance, and potential strategies for ...
Mozaffar Abdollahifar, Andrea Paolella
wiley   +1 more source

Synthesis and application of polyoxometalate ionic liquid-coated ZnO nanoflowers for efficient extraction of tetracycline residues in food and environmental samples. [PDF]

RSC Adv
Nazar Z, Al-Hmoud M, Tahroudi ZM, Suvorova A, Khan MS, Binzowaimil AM, Ahmad H, Irfan A.   +7 more
europepmc   +1 more source