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Chiral analysis by nano-liquid chromatography

TrAC Trends in Analytical Chemistry, 2020
The concept of stereoisomerism in the biological activity of compounds in living systems emerged in 1948 with the work of Louis Pasteur, who first observed the optical activity of tartaric acid. Enantiomers can produce undesired effects on biological system, due to their different optical activity, even though they possess the same physico-chemical ...
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A JOURNEY FROM MIKHAIL TSWETT TO NANO-LIQUID CHROMATOGRAPHY

Journal of Liquid Chromatography & Related Technologies, 2010
Today, chromatography is the back bone of separation science and is being used in all research laboratories and industries of the world. It has developed into nano liquid chromatography (NLC) modality through various kinds of chromatography. The present article describes a journey from Mikhail Tswett in 1903 to today of NLC.
Imran Ali   +2 more
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Analysis of phytosterols in extra-virgin olive oil by nano-liquid chromatography

Journal of Chromatography A, 2009
In this work the applicability of nano-liquid chromatography (nano-LC) was evaluated for the determination of phytosterols in extra-virgin olive oil samples. These compounds represent a minor part of lipids in vegetable oils, but their quantification can be useful to establish oil origin and to reveal intentional adulterations.
Anna Rocco, Salvatore Fanali
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Nano-liquid chromatography in nutraceutical analysis: Determination of polyphenols in bee pollen

Journal of Chromatography A, 2013
In this study, a nano-liquid chromatography based method for the simultaneous separation of 16 polyphenols employing UV-vis detection has been developed. A 100 μm I.D. capillary column packed with C18 core-shell particles (2.6 μm particle size, 100 Å) for 10 cm was employed.
C Fanali, L Dugo, A Rocco
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Analysis of synthetic cannabinoids in herbal blends by means of nano-liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis, 2012
In this study, a rapid and simultaneous separation of 12 synthetic cannabinoids and Δ(9)-tetrahydrocannabinol (Δ(9)-THC) in herbal blends was obtained by means of nano-liquid chromatography (nano-LC). The nano-LC experiments were performed in a 100μm i.d. capillary column packed with Cogent(®) bidentate C(18) silica particles for 25.0cm.
G Merola   +6 more
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Use of micro, capillary, and nano liquid chromatography for forensic analysis

Journal of Separation Science, 2021
AbstractThe use of micro, capillary, and nano liquid chromatography systems for forensic analysis has excellent potential. In a field where sample size is often limited, several studies have presented the viability of capillary columns with microflow and nanoflow, and when using mass spectrometric analysis limits of detection can be improved. Reduction
Joel B. Langford, Ira S. Lurie
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Separation of organophosphorus pesticides by using nano-liquid chromatography

Journal of Chromatography A, 2009
In the present research, the separation of a series of organophosphorus pesticides (fensulfothion, fenamiphos, profenofos, fonofos, isofenphos, dialifos, sulprofos and prothiofos), by using nano-liquid chromatography (nano-LC) with UV detection is described. Three 100 microm ID capillary columns, packed with different silica-based stationary phases (CN,
Katia Buonasera   +4 more
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Simplified gradient generator for micro- and nano-liquid chromatography

Journal of Chromatography A, 2006
We have developed a simple device to generate gradient elution profiles using split tubing array (STAR) units for micro- and nano-HPLC. This gradient device consists of a delivery pump, a splitter, tubes in parallel, and a relatively large-volume mixing chamber.
Kaoru, Murata   +3 more
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A Newcomer’s Guide to Nano-Liquid-Chromatography of Peptides

2009
LC-MS/MS is one of the most powerful techniques in the field of proteomics allowing high throughput identification of proteins out of complex protein mixtures. Besides high sample throughput, the analytical sensitivity is one of the major benefits of this technology.
Thomas, Fröhlich, Georg J, Arnold
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Chiral Separations Using Nano-Liquid Chromatography

Scientia Chromatographica, 2016
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Chiara Fanali   +2 more
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