Chitosan-Based Nanocarriers for Nose to Brain Delivery
In the treatment of brain diseases, most potent drugs that have been developed exhibit poor therapeutic outcomes resulting from the inability of a therapeutic amount of the drug to reach the brain.
Blessing Atim Aderibigbe, Tobeka Naki
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Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
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Macrophages are involved in the whole process of atherosclerosis, which is characterized by accumulation of lipid and inflammation. Presently, clinically used lipid-lowering drugs cannot completely retard the progress of atherosclerosis. Liver X receptor
Tong-Mei Yang +6 more
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Can pulsed electromagnetic fields trigger on-demand drug release from high-tm magnetoliposomes? [PDF]
Recently, magnetic nanoparticles (MNPs) have been used to trigger drug release from magnetoliposomes through a magneto-nanomechanical approach, where the mechanical actuation of the MNPs is used to enhance the membrane permeability.
Apollonio, Francesca +7 more
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Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. [PDF]
Nanocarriers can deliver a wide variety of drugs, target them to sites of interest, and protect them from degradation and inactivation by the body. They have the capacity to improve drug action and decrease undesirable systemic effects.
Bratt, Jennifer M +6 more
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Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Höltje, H.-D. +3 more
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Innovative nanocarriers: Synthetic and biomimetic strategies for enhanced drug delivery
Effective drug delivery plays a vital role in the treatment of various biomedical conditions. Application of innovative nanocarriers could address issues faced in drug delivery such as poor drug distribution, inefficient penetration across biological ...
Runzi Guo +8 more
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Decoration of nanovesicles with pH (low) insertion peptide (pHLIP) for targeted delivery [PDF]
Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells.
Andreev O. A. +9 more
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Chitosan-g-oligo(epsilon-caprolactone) polymeric micelles: microwave-assisted synthesis and physicochemical and cytocompatibility characterization [PDF]
With the aim to produce mucoadhesive polymeric micelles for drug administration by mucosal routes, chitosan-g-oligo(epsilon-caprolactone) copolymers were synthesized by the microwave-assisted ring-opening polymerization of epsilon-caprolactone using ...
Calderon, Marcelo +5 more
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Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
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