Results 51 to 60 of about 69,654 (255)

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão   +5 more
wiley   +1 more source

Research progress on using responsive nanocarriers to deliver drugs for cancer therapy

open access: yes上海师范大学学报. 自然科学版
Recently, nanocarriers have received widespread attention in the field of drug and functional nucleic acid delivery due to their excellent loading capacity, efficient delivery performance, and precise targeting.
ZHU Qingyun, SU Danyang, CHEN Nan
doaj   +1 more source

Dextran-based Nanocarriers as Efficient Media Delivery Vehicles to Cell Production Bioreactors

open access: yesNano Biomedicine and Engineering, 2010
Decreasing the volume of media required to maintain cell viability not only reduces contamination of bioreactors from the upstream process, but may contribute to cost-containment measures in the biopharmaceutical industry.
Edmund Anton   +3 more
doaj   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang   +5 more
wiley   +1 more source

pH-Responsive Nanocarriers for Cancer Therapy [PDF]

open access: yes, 2022
There are currently several strategies that are used to treat cancer including surgery, chemotherapy and radiotherapy. However, conventional chemotherapeutics suffer from a number of limitations, such as poor solubility, short in vivo circulation half ...
Kalmouni, Mona
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

Current Knowledge and Future Perspectives of Exosomes as Nanocarriers in Diagnosis and Treatment of Diseases

open access: yes, 2023
Zaijun Zou,1,2 Han Li,1,2 Gang Xu,1,3 Yunxiang Hu,2 Weiguo Zhang,1,3 Kang Tian1,3 1Department of Sports Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2School of Graduates ...
Zhang W, Li H, Tian K, Zou Z, Hu Y, Xu G
core  

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

open access: yesAdvanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol   +16 more
wiley   +1 more source

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