Results 81 to 90 of about 69,654 (255)

Liposomes to cubosomes: The evolution of lipidic nanocarriers and their cutting-edge biomedical applications [PDF]

Lipidic nanoparticles have undergone extensive research towards the exploration of their diversely ranging therapeutic applications. Although several liposomal formulations are in the clinics (e.g., DOXIL) for cancer therapy there are many challenges ...
Jhimli, Banerjee, Nishtha, Attri, Swarnali, Das, Shazana H., Shamsuddin, ARINDAM, PRAMANIK, Sandeep, Kumar Dash   +5 more
core   +1 more source

Rapid synthesis of multifunctional β-cyclodextrin nanospheres as alkali-responsive nanocarriers and selective antibiotic adsorbents

, 2021
Novel hypercross-linked β-cyclodextrin nanospheres are rapidly synthesized with 4-amino-6-hydroxy-2-mercaptopyrimidine as a cross-linker within 5 min at a low temperature of 60 °C in the open water phase, thereby radically simplifying and accelerating ...
Fang, Xian, Liu, Ying, Li, Zhuo, Zong, Boyang, Li, Qiuju, Mao, Shun, Wang, Dandan, Ostrikov, Kostya Ken   +7 more
core   +1 more source

A systematic review of nanocarriers used in medicine and beyond — definition and categorization framework

Journal of Nanobiotechnology
Nanocarriers are transport and encapsulation systems that primarily serve to protect and improve the dispersibility of predominantly hydrophobic active ingredients but also enable their targeted delivery and controlled release at the site of action ...
Sabine Gressler, Christina Hipfinger, Florian Part, Anna Pavlicek, Christian Zafiu, Bernd Giese   +5 more
doaj   +1 more source

Porous α-Fe2O3 nanocarriers: Biosynthesis and in vitro gene delivery applications

Heliyon
Non-viral gene delivery is a new therapeutic in the treating genetic disorders. The most important challenge in nonviral gene transformation is the immunogenicity of carriers.
Hajar Q. Alijani, Shahram Pourseyedi, Masoud Torkzadeh-Mahani, Mehrdad Khatami   +3 more
doaj   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Biomimetic nanocarriers in cancer therapy: based on intercellular and cell-tumor microenvironment communication

Journal of Nanobiotechnology
Inspired by the concept of “natural camouflage,” biomimetic drug delivery systems have emerged to address the limitations of traditional synthetic nanocarriers, such as poor targeting, susceptibility to identification and clearance, inadequate ...
He Mengyuan, Li Aixue, Gu Yongwei, Chai Qingqing, Cai Huanhuan, Liu Xiaoyan, Liu Jiyong   +6 more
doaj   +1 more source

CD44 targeted functionalized nanocarriers for non-small cell lung cancer

Frontiers in Oncology
Non-small cell lung cancer (NSCLC) is a significant worldwide health concern, requiring novel treatment strategies. This review presents the potential of CD44-targeted functionalized nanocarriers as effective tools for treating NSCLC.
Na Zhu, Ruijuan Guo, Yanyan Jiang, Mingling Xu   +3 more
doaj   +1 more source

Association of Alpha Tocopherol and Ag Sulfadiazine Chitosan Oleate Nanocarriers in Bioactive Dressings Supporting Platelet Lysate Application to Skin Wounds

Marine Drugs, 2018
Chitosan oleate was previously proposed to encapsulate in nanocarriers some poorly soluble molecules aimed to wound therapy, such as the anti-infective silver sulfadiazine, and the antioxidant α tocopherol.
Maria Cristina Bonferoni, Giuseppina Sandri, Silvia Rossi, Eleonora Dellera, Alessandro Invernizzi, Cinzia Boselli, Antonia Icaro Cornaglia, Claudia Del Fante, Cesare Perotti, Barbara Vigani, Federica Riva, Carla Caramella, Franca Ferrari   +12 more
doaj   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source