Results 131 to 140 of about 12,080 (272)

Engineered an Ultrasmall Curcumin Oral Nanoformulation Restores Intestinal Integrity and Gut Microbiota Dysbiosis

Antibiotic therapy for bacterial infections often disrupts gut microbiota (GM) and intestinal integrity, inducing chronic inflammation and inflammatory bowel diseases.
Gupta, Sateesh, Barik, Saroj, Prateeksha, Prateeksha, Agrahari, Sushil, Anunay, Anand, Singh, Sarvendra, Singh, Shailendra, Sharma, Vivek, Paliya, Balwant, Singh, Brahma, Rao, Chandana   +10 more
core   +1 more source

Effect of the nanoformulation of siRNA-lipid assemblies on their cellular uptake and immune stimulation

, 2017
Kohei Kubota,1,2 Kohei Onishi,3 Kazuaki Sawaki,3 Tianshu Li,4 Kaoru Mitsuoka,5 Takaaki Sato,6 Shinji Takeoka1,3,4 1Cooperative Major in Advanced Biomedical Sciences, Graduate School of Advanced Sciences and Engineering, Waseda University (TWIns), Tokyo,
Kubota K, Sato T, Mitsuoka K, Li T, Sawaki K, Onishi K, Takeoka S   +6 more
core  

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Zn2+‐Driven Self‐Amplifying Nanoplatform Enables Cascade Photothermal–Gene Therapy via Mitochondrial Disruption

VIEW, EarlyView.
A Zn2+‐activated nanoplatform enables self‐amplifying photothermal–gene therapy by disrupting mitochondria and releasing siRNA, creating a feedback loop that sensitizes tumor cells and enhances ablation in vitro and in vivo. This metal ion‐driven strategy offers a new approach for cascade‐amplified nanotherapeutics. ABSTRACT The therapeutic efficacy of
Zhi Li, Yuhong Chen, Youfei Zhang, Luzhen Huai, Xingzhou Zhu, Xue Mo, Jiahao Wang, Kui Zeng, Jie Wang   +8 more
wiley   +1 more source

Melatonin-Polydopamine Nanoformulation Prevents Retinal Neurodegeneration in a Preclinical Model of Diabetic Retinopathy

Reactive oxygen species, inflammation, angiogenesis, and retinal neurodegeneration lead to diabetic retinopathy (DR) progression. The inhibition of VEGF and prevention from retinal neurodegeneration pave the way to developing DR treatment. Melatonin is a
Vikas Kumar Sahu (18297038), Mrunalini Boddu (12524136), Surajit Karmakar (1366047), Subhasree Roy Choudhury (5679161), Mohammed Nadim Sardoiwala (8762409), Liku Biswal (14700735)   +5 more
core   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Hytrin Nanoformulation Reduces Nitrated Synucleinopathy Through Chaperon-Mediated Autophagy

The loss of dopaminergic neurons, majorly due to synucleinopathy, is the prime cause of Parkinson’s disease (PD) progression. Like phosphorylated synuclein, nitrated synuclein also significantly contributes to Lewy body formation in the PD etiology ...
Mrunalini Boddu (12524136), Surajit Karmakar (1366047), Subhasree Roy Choudhury (5679161), Mohammed Nadim Sardoiwala (8762409), Liku Biswal (14700735)   +4 more
core   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, Volume 41, Issue 10, Page 957-974, October 2026.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

ST8 micellar/niosomal vesicular nanoformulation for delivery of naproxen in cancer cells: Physicochemical characterization and cytotoxicity evaluation

, 2020
Naproxen (NPX) is a non-steroidal anti-inflammatory drug (NSAID) used against a variety of diseases, including autoimmune disorders and chronic inflammations.
Balakheyli, H., Shirvani, S., Aghaei, M., Erfani-Moghadam, V., Abdolahi, N., Ravaghi, A., Soltani, A., Cordani, M., Rad, S.M.   +8 more
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