Results 121 to 130 of about 14,638 (259)

Innovations in the Delivery of Bioactive Compounds for Cancer Prevention and Therapy: Advances, Challenges, and Future Perspectives

Pharmaceuticals
Naturally occurring bioactive compounds represent a promising option for cancer prevention and therapy due to their ability to modulate apoptosis, angiogenesis, inflammation, oxidative stress, and cell signaling. However, their clinical impact is limited
Carlos A. Ligarda-Samanez, Mary L. Huamán-Carrión, Jackson M’coy Romero Plasencia, Dante Fermín Calderón Huamaní, Bacilia Vivanco Garfias, Jenny C. Muñoz-Saenz, Maria Magdalena Bautista Gómez, Jaime A. Martinez-Hernandez, Wilber Cesar Calsina-Ponce   +8 more
doaj   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Citrus Essential Oils in Food Safety and Health: Advances in AI‐Assisted Authentication, Antimicrobial Applications, Sustainable Extraction, and Regulatory Translation

Food Safety and Health, EarlyView.
Citrus essential oils combine sustainable extraction, AI‐assisted authentication, multi‐omics profiling, antimicrobial activity, and regulatory safety to enhance food quality, detect adulteration, and promote consumer health, and support intelligent, sustainable food systems through innovative industrial applications and circular bioeconomy strategies.
Md. Hassan Bin Nabi, Liza Akter, Yusuf Chowdhury, Mohima Akther Any, Nazmul Islam, Erni Sofia Murtini, Nurul Huda, Wahidu Zzaman   +7 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Nanoformulations of Pretilachlor Herbicide: Preparation, Characterization and Activity [PDF]

, 2016
676-680In the present study, two nanoformulations of pretilachlor: microemulsion (ME) and encapsulated monolithic dispersion (MD) have been developed. Both the formulations were tested for their stability and found to be stable at different temperature ...
Das, T K, Shakil, N A, Kumar, R, Kumar, N   +3 more
core  

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This study aims to synthesize and characterize lipid nanosystems (liposomes) for the incorporation of a Zn(II) porphyrin derivative, Zn(II) meso‐tetrakis(N‐n‐hexylpyridinium‐2‐yl)porphyrin (ZnTnHex‐2‐PyP4+, ZnPH), intending to employ an alternative method of treatment, such as photodynamic therapy (PDT), for breast cancer (BC ...
Kammila Martins Nicolau Costa, José Ferreira Sarmento‐Neto, Júlio Santos Rebouças, Ricardo Olímpio de Moura, John F. Callan, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

The significance of the protein corona in orally administered nanoformulations

Suun kautta annosteltavien nanoformulaatioiden avulla voidaan parantaa lääkeaineiden kuljetusta, kohdentamista ja biologista hyötyosuutta. Nanoformulaatioiden pinnalle adsorboituu ruoansulatuskanavassa proteiineja, jotka muodostavat proteiinikoronan, ja ...
Kangastupa, Jenny
core  

From essential oils to integrated storage systems: strategies for fungal and mycotoxin control in post-harvest cereals – a systematic review and bibliometric analysis

Notulae Scientia Biologicae
Post-harvest fungal contamination of cereals represents a major challenge to global food security because it reduces grain quality and increases the risk of mycotoxin contamination.
Salma Astati, Laila Rhazi, Salma Bakhchou, Douniya Tallal, Imane Wahby   +4 more
doaj   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source