Results 91 to 100 of about 3,520 (152)

A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins. [PDF]

Elife
Kelpsch DJ, Zhang L, Thierer JH, Rivera Cruz AG, Koren K, Kumar U, Lin Y, Hensley MR, Sohn M, Liu JO, Lectka T, Mumm JS, Farber SA.   +12 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy. [PDF]

Ann Clin Transl Neurol
Saravanan A, Safran J, Loughman A, Lin G, Vaid S, Allababidi D, Tessier PM, Dang LT.   +7 more
europepmc   +1 more source

Rapid, expression-free bacteriophage-based specific detection of target bacteria by conditional release of encapsidated reporter molecules. [PDF]

Bioeng Transl Med
Avramucz Á, Wheatley JP, Liyanagedera SBW, Fehér T, Amaee R.   +4 more
europepmc   +1 more source

The Chemerin Receptor CMKLR1 Requires Full-Length Chemerin for High Affinity in Contrast to GPR1 as Demonstrated by a New Nanoluciferase-Based Binding Assay

To study the binding mode of the adipokine chemerin as well as the short peptide agonist chemerin-9 (C9) to its two receptors chemokine-like receptor 1 (CMKLR1) and G protein-coupled receptor 1 (GPR1), we generated 5-carboxytetramethylrhodamine (TAMRA ...
Beck-Sickinger, Annette G., Kretschmer, Kevin, Czerniak, Anne Sophie, Weiß, Tina   +3 more
core   +1 more source

Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation. [PDF]

Nucleic Acids Res
Wieland CM, Wright SE, Willey S, Purwar I, Grudzien SJ, Krans A, Laimon EL, Asher MJ, Isaacs AM, Garner AL, Todd PK.   +10 more
europepmc   +1 more source

Sweet and Bright: Illuminating Glycoprotein-Mediated Endocytosis via Metabolic Labeling and NanoLuciferase. [PDF]

ACS Chem Biol
Soliman MO, Koivuniemi A, Freiburghaus V, Garbujo S, Urech L, Frascotti G, Prosperi D, Colombo M, Hanzlikova M, Hartrampf N, Laaksonen T, Wang S.   +11 more
europepmc   +1 more source

Hesperetin and Naringenin promote glucagon-like peptide-1 secretion from L-cell through activation of TGR5 and alleviated type 2 diabetes. [PDF]

Front Pharmacol
Zhang CY, Wang ZL, Jiang ZJ, Kim H, Liu C, Wang H.   +5 more
europepmc   +1 more source

Co-Translational Incorporation of (<i>R</i>)- and (<i>S</i>)-β²-Hydroxyacids <i>In Vivo</i>: Directed Evolution of Efficient Aminoacyl-tRNA Synthetases. [PDF]

J Am Chem Soc
Soni C, Pressimone M, Nair M, Szalay K, Hall M, Hamlish N, Solivan AC, Schepartz A, Chatterjee A.   +8 more
europepmc   +1 more source

High-throughput assay for measuring target occupancy of covalent compounds: a case study with MK2. [PDF]

RSC Chem Biol
Wong JL, Manuia M, Gao S, Stoehr N, Boersig T, Vuong K, Jiang T, Cao J, Jia Y, King CC, Joslin J, Ofori L, Loren J, Bassi ZI.   +13 more
europepmc   +1 more source

A Structure-guided Active Site Affinity Ligand Unmasks a Stress-Sensitizing Role for BLVRB in the Endoplasmic Reticulum. [PDF]

J Med Chem
Thekke Veedu RR, Sheriff J, Nesbitt NM, Marchenko N, Pennacchia L, Ginex T, Hearing P, Kreitler DF, Bahou WF.   +8 more
europepmc   +1 more source