Results 1 to 10 of about 58 (35)

Polymer-Based Smart Drug Delivery Systems for Skin Application and Demonstration of Stimuli-Responsiveness. [PDF]

Polymers (Basel), 2021
Van Gheluwe L, Chourpa I, Gaigne C, Munnier E.   +3 more
europepmc   +1 more source

Model Affitin and PEG modifications onto siRNA lipid nanocapsules: cell uptake and in vivo biodistribution improvements. [PDF]

RSC Adv, 2019
Resnier P, Lepeltier E, Emina AL, Galopin N, Bejaud J, David S, Ballet C, Benvegnu T, Pecorari F, Chourpa I, Benoit JP, Passirani C.   +11 more
europepmc   +1 more source

Locoregional Confinement and Major Clinical Benefit of ¹⁸⁸Re-Loaded CXCR4-Targeted Nanocarriers in an Orthotopic Human to Mouse Model of Glioblastoma. [PDF]

Theranostics, 2017
Séhédic D, Chourpa I, Tétaud C, Griveau A, Loussouarn C, Avril S, Legendre C, Lepareur N, Wion D, Hindré F, Davodeau F, Garcion E.   +11 more
europepmc   +1 more source

Specific Cell Targeting by Toxoplasma gondii Displaying Functional Single-Chain Variable Fragment as a Novel Strategy; A Proof of Principle. [PDF]

Cells
Aljieli M, Rivière C, Lantier L, Moiré N, Lakhrif Z, Boussemart AF, Cnudde T, Lajoie L, Aubrey N, Ahmed EM, Dimier-Poisson I, Di-Tommaso A, Mévélec MN.   +12 more
europepmc   +1 more source

Formulation of Lipid-Based Nanoparticles for Simultaneous Delivery of Lapatinib and Anti-Survivin siRNA for HER2+ Breast Cancer Treatment [PDF]

Pharmaceuticals, 2022
In this work, lipid-based nanoparticles (LBNP) were designed to combine tyrosine kinase inhibitor (TKI) Lapatinib (LAPA) with siRNA directed against apoptosis inhibitor protein Survivin (siSurvivin) in an injectable form.
Sahar Eljack, Stephanie David, Igor Chourpa, Areeg Faggad, Emilie Allard-Vannier   +4 more
doaj   +2 more sources

Combination of Nanovectorized siRNA Directed against Survivin with Doxorubicin for Efficient Anti-Cancer Activity in HER2+ Breast Cancer Cells [PDF]

Pharmaceutics, 2022
According to Globocan 2020, breast cancer is considered one of the most common cancers affecting women and is one of the leading causes of death in over 100 countries.
Sahar Eljack, Emilie Allard-Vannier, Yoann Misericordia, Katel Hervé-Aubert, Nicolas Aubrey, Igor Chourpa, Areeg Faggad, Stephanie David   +7 more
doaj   +2 more sources

In vitro synergistic activity of cisplatin and EGFR-targeted nanomedicine of anti-Bcl-xL siRNA in a non-small lung cancer cell line model [PDF]

International Journal of Pharmaceutics: X, 2022
Apoptosis is an important process that directly affects the response of cancer cells to anticancer drugs. Among different factors involved in this process, the BcL-xL protein plays a critical role in inhibiting apoptosis induced by chemotherapy agents ...
Phuoc Vinh Nguyen, Katel Hervé-Aubert, Laurie Lajoie, Yoann Misericordia, Igor Chourpa, Stéphanie David, Emilie Allard-Vannier   +6 more
doaj   +2 more sources

Formation of miRNA Nanoprobes—Conjugation Approaches Leading to the Functionalization [PDF]

Molecules, 2022
Recently, microRNAs (miRNA) captured the interest as novel diagnostic and prognostic biomarkers, with their potential for early indication of numerous pathologies.
Iveta Vilímová, Katel Hervé-Aubert, Igor Chourpa   +2 more
doaj   +2 more sources

Estimating the Analytical Performance of Raman Spectroscopy for Quantification of Active Ingredients in Human Stratum Corneum [PDF]

Molecules, 2022
Confocal Raman microscopy (CRM) has become a versatile technique that can be applied routinely to monitor skin penetration of active molecules. In the present study, CRM coupled to multivariate analysis (namely PLSR—partial least squares regression) is ...
Hichem Kichou, Emilie Munnier, Yuri Dancik, Kamilia Kemel, Hugh J. Byrne, Ali Tfayli, Dominique Bertrand, Martin Soucé, Igor Chourpa, Franck Bonnier   +9 more
doaj   +2 more sources