Results 101 to 110 of about 105,790 (331)

Multifunctional Applications of Extracellular Nanovesicles for Acute Kidney Injury and Renal Fibrosis; a Mini Review

International Journal of Nanomedicine
Ruizhe Xu,1 Shuainan Liu,2 Zhenhua Cui1 1Department of Nephrology, College of Medicine, Yanbian University, Yanji, Jilin, 133000, People’s Republic of China; 2Department of Dermatology, College of Medicine, Yanbian University, Yanji, Jilin, 133000 ...
Xu R, Liu S, Cui Z
doaj  

The landscape of mRNA nanomedicine

Nature Medicine, 2022
Xiangang Huang, Na Kong, Xingcai Zhang, Yihai Cao, R. Langer, Wei Tao   +5 more
semanticscholar   +1 more source

The Distribution of Complement Proteins in Soft and Hard Coronas Impacts Macrophage Uptake of Nanoparticles

Advanced Healthcare Materials, EarlyView.
Protein corona plays a critical role in the biological behavior of nanoparticles. This study investigates the distribution of complement proteins in soft corona and their impact on the macrophage uptake of polymer nanoparticles. It underlines the significance of soft corona investigation for understanding in vivo performance of nanomedicines.
Ying Qiu, Tianchang He, Chunjie Miao, Xinyang Shi, Yuanyuan Niu, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

A novel pH-sensitive nanoparticles encapsulating anti-PD-1 antibody and MDK-siRNA overcome immune checkpoint blockade resistance in HCC via reshaping immunosuppressive TME

Journal of Experimental & Clinical Cancer Research
Objective Immunotherapy, notably the immune checkpoint blockade (ICB), has demonstrated significant promise in the management of diverse neoplasms. However, the PD-1 inhibitor has exhibited suboptimal objective response rates and did not achieve the ...
Hai Xu, Shuo Li, Yifan Liu, Yoon-Young Sung, Yong Zhou, Huikun Wu   +5 more
doaj   +1 more source

Rapid and scalable detection of synthetic mRNA byproducts using polynucleotide phosphorylase and polythymidine oligonucleotides

RNA Biology
Production and storage of synthetic mRNA can introduce a variety of byproducts which reduce the overall integrity and functionality of mRNA vaccines and therapeutics.
Francis Combes, Thanh-Huong Bui, Frida J. Pettersson, Sjoerd Hak   +3 more
doaj   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery

Frontiers in Pharmacology, 2017
Nanomedicines including liposomes, micelles, and nanoparticles based on the enhanced permeability and retention (EPR) effect have become the mainstream for tumor treatment owing to their superiority over conventional anticancer agents. Advanced design of
Bo Zhang, Bo Zhang, Yu Hu, Zhiqing Pang
doaj   +1 more source

Diverse Applications of Nanomedicine

ACS Nano, 2017
The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest.
B. Pelaz, C. Alexiou, R. Álvarez-Puebla, F. Alves, A. M. Andrews, Sumaira Ashraf, L. Balogh, L. Ballerini, A. Bestetti, C. Brendel, S. Bosi, M. Carril, W. Chan, Chunying Chen, Xiaodong Chen, Xiaoyuan Chen, Zhen Cheng, D. Cui, Jianzhong Du, C. Dullin, A. Escudero, N. Feliu, Mingyuan Gao, M. George, Y. Gogotsi, A. Grünweller, Z. Gu, N. Halas, N. Hampp, R. Hartmann, M. Hersam, P. Hunziker, Ji Jian, Xingyu Jiang, P. Jungebluth, Pranav Kadhiresan, K. Kataoka, A. Khademhosseini, J. Kopeček, N. Kotov, H. Krug, D. S. Lee, C. Lehr, K. Leong, Xing-jie Liang, Mei Ling Lim, L. Liz‐Marzán, Xiaowei Ma, P. Macchiarini, Huan Meng, H. Möhwald, P. Mulvaney, A. Nel, S. Nie, P. Nordlander, T. Okano, J. Oliveira, T. Park, R. Penner, M. Prato, V. Puntes, V. Rotello, Amila Samarakoon, R. Schaak, Youqing Shen, Sebastian Sjöqvist, A. Skirtach, Mahmoud Soliman, M. Stevens, Hsing‐Wen Sung, B. Tang, R. Tietze, Buddhisha N Udugama, J. VanEpps, T. Weil, P. Weiss, I. Willner, Yuzhou Wu, Lily Yang, Zhao Yue, Qian Zhang, Qiang Zhang, Xian-En Zhang, Yuliang Zhao, Xin Zhou, W. Parak   +85 more
semanticscholar   +1 more source

Recent Advancements of Anti-cancer Nanomedicine in Breast Cancer

, 2022
Jiachen Li
openalex   +1 more source