Results 181 to 190 of about 95,094 (198)

Clinical Applications of Targeted Nanomaterials. [PDF]

Pharmaceutics
Kumar A, Shahvej SK, Yadav P, Modi U, Yadav AK, Solanki R, Bhatia D.   +6 more
europepmc   +1 more source

Artificial Intelligence Advancements in Oncology: A Review of Current Trends and Future Directions. [PDF]

Biomedicines
Huhulea EN, Huang L, Eng S, Sumawi B, Huang A, Aifuwa E, Hirani R, Tiwari RK, Etienne M.   +8 more
europepmc   +1 more source

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Nanomedicine‐Enabled Sonomechanical, Sonopiezoelectric, Sonodynamic, and Sonothermal Therapy

Advances in Materials, 2023
Nanomedicine‐enabled/augmented ultrasound (US) medicine is a unique area of interdisciplinary research that focuses on designing and engineering functional nanosystems to address the challenging issues in US‐based biomedicine, overcoming the shortcomings
Xinran Song, Qin Zhang, Meiqi Chang, Li Ding, Hui Huang, Wei Feng, Tianming Xu, Yu Chen   +7 more
semanticscholar   +1 more source

Tumor Abnormality-Oriented Nanomedicine Design.

Chemical Reviews, 2023
Anticancer nanomedicines have been proven effective in mitigating the side effects of chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic efficacy.
Quan Zhou, Jiajia Xiang, Nasha Qiu, Yechun Wang, Ying Piao, Shiqun Shao, Jianbin Tang, Zhuxian Zhou, Youqing Shen   +8 more
semanticscholar   +1 more source

Human solid tumors and clinical relevance of the enhanced permeation and retention effect: a 'golden gate' for nanomedicine in preclinical studies?

Nanomedicine, 2023
Nanocarriers passively accumulate in solid tumors through irregular wide fenestrations in neovasculature and increased retention due to poor lymphatic drainage, a phenomenon termed the enhanced permeation and retention (EPR) effect.

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Chemical and Biophysical Signatures of the Protein Corona in Nanomedicine.

Journal of the American Chemical Society, 2022
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous collection of biomolecular species by nanoparticles in living systems.
Jiayu Ren, N. Andrikopoulos, K. Velonia, Huayuan Tang, Rong Cai, F. Ding, P. Ke, Chunying Chen   +7 more
semanticscholar   +1 more source

Reactive Oxygen Species (ROS)-Based Nanomedicine.

Chemical Reviews, 2019
Reactive oxygen species (ROS) play an essential role in regulating various physiological functions of living organisms. The intrinsic biochemical properties of ROS, which underlie the mechanisms necessary for the growth, fitness, or aging of living ...
Bowen Yang, Yu Chen, Jianlin Shi
semanticscholar   +1 more source

Engineering nanomedicine for glutathione depletion-augmented cancer therapy.

Chemical Society Reviews, 2021
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator of tumor initiation, progression and metastasis. It is also implicated in the resistance of platinum-based chemotherapy and radiation therapy.
Yuxuan Xiong, C. Xiao, Zifu Li, Xiangliang Yang   +3 more
semanticscholar   +1 more source

Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.

ACS Nano, 2022
The nanocatalytic activity of nanozymes provides a vision for tumor treatment. However, the glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of excessive GSH in the tumor microenvironment limits its catalytic activity. Here,
Feng Wu, Yaqian Du, Jiani Yang, Boyang Shao, Zhensheng Mi, Yuanfei Yao, Ying Cui, Fei He, Yanqiao Zhang, Piaoping Yang   +9 more
semanticscholar   +1 more source

Theranostic nanomedicine.

Accounts of Chemical Research, 2020
Nanomedicine formulations aim to improve the biodistribution and the target site accumulation of systemically administered (chemo)therapeutic agents.
T. Lammers, S. Aime, W. Hennink, G. Storm, F. Kiessling   +4 more
semanticscholar   +1 more source