Results 101 to 110 of about 1,679 (212)

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

Molecular Therapy: Nucleic Acids, 2019
Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans.
Chin-Yu Lin, Samuel Thomas Crowley, Satoshi Uchida, Yuji Komaki, Kazunori Kataoka, Keiji Itaka   +5 more
doaj   +1 more source

Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu, Yi‐Tung Lu, Bin Yang, Zhi Li, Kui Zeng   +4 more
wiley   +1 more source

A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution

, 2012
Mingshu Ma,1 Yanli Hao,1 Nan Liu,1 Zhe Yin,1 Lan Wang,1 Xingjie Liang,2 Xiaoning Zhang11Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, China; 2National Center for Nanoscience and Technology ...
Ma M, Liang X, Liu N, Zhang X, Hao Y, Yin Z, Wang L   +6 more
core  

Terapia topica del melanoma cutaneo: nuovi formulati a base di nanomicelle Ph-sensibili

, 2020
Il lavoro della presente tesi si è basato sulla preparazione e caratterizzazione di nanomicelle contenenti Imiquimod per la terapia topica degli stati precancerosi e del cancro della pelle, con l'obiettivo di mettere a punto un sistema drug-delivery in ...
VERGAZZOLI, MATTIA
core  

Development of great burdock essence compounds

, 2012
The nanomicelle encapsulating the water-insoluble substances can solubilize in aqueous solution. In this study, we used nanomicelle technology to develop great burdock essence.
Ching-Hui Wang;Fu-Yen Chung;Tong-Rong Tsai;Shiu-Ru Lin;Hsueh-Chiao Liu
core   +2 more sources

Enhanced Tumor Penetration and Chemotherapy Efficiency by Covalent Self-Assembled Nanomicelle Responsive to Tumor Microenvironment

, 2019
The physicochemical properties of nanomedicine can be altered with a tumor microenvironment, which influence the precise delivery of drug molecules to the lesion. Thus, the therapeutic efficiency is restrained. Here, a covalent self-assembled nanomicelle
Yuejun Kang (613140), Xianbin Ma (6823604), Jinjun Shao (2226739), Xiaoqian Ma (263972), Xiaoli Zhang (135098), Xiaoxiao Shi (109071), Zhigang Xu (378834), Shuang Bai (428404), Die Jia (6823607), Peng Xue (219948)   +9 more
core   +1 more source

Formulation and Evaluation of Lercanidipine HCL Loaded Nanomicelles

Iraqi Journal of Pharmaceutical Sciences
Among the strong calcium channel blockers, lercanidipine hydrochloride (LER) has been shown to be useful in reducing blood pressure by acting on L-type calcium channels.
Hala Mohammed Fatih, Kawther Khalid Ahmed   +1 more
doaj   +1 more source

Nanomicelle drug with acid-triggered doxorubicin release and enhanced cellular uptake ability based on mPEG-graft-poly(N-(2-aminoethyl)-L-aspartamide)-hexahydrophthalic acid copolymers

, 2017
In order to achieve the passive tumor targeting and acid-triggered drugs release in lysosomes, optimized delivery system for doxorubicin based on pH-sensitive complex nanomicelles with suitable particle size was developed in this research. Particularly,
Lin Gan, Jin Huang, Li Cao, Jiahui Yu, Wei Lu, Yi Xiao, Shiyuan Liu   +6 more
core   +1 more source

Cationic nanomicelles derived from Pluronic F127 as delivery vehicles of Chinese herbal medicine active components of ursolic acid for colorectal cancer treatment

, 2018
A cationic nanomicelle derived from Pluronic F127 as a delivery vehicle of ursolic acid for enhanced colorectal cancer treatment.
Xiaolong Liu, Zhaokun Yan, Ming Wu, Qin Li, Jun Peng, Qingtang Wang, Jiumao Lin   +6 more
core   +1 more source

A multifunctional nanomicelle for real-time targeted imaging and precise near-infrared cancer therapy

, 2014
Simultaneous targeted cancer imaging, therapy and real-time therapeutic monitoring can prevent over- or undertreatment. This work describes the design of a multifunctional nanomicelle for recognition and precise near-infrared (NIR) cancer therapy.
Yang, Chaoyong James, 杨朝勇, Li, Xilan, Zhu, Zhi, Yang, Yongchao, Ju, Huangxian, Tian, Jiangwei, Yu, Jun-Sheng, Ding, Lin, Shen, Zhen, 朱志   +10 more
core