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Advanced nanomicelles for targeted glioblastoma multiforme therapy
Biomaterials AdvancesGlioblastoma multiforme (GBM) is the most aggressive and malignant primary brain tumor, classified as grade IV by the WHO. Despite standard treatments like surgical resection, radiotherapy and chemotherapy (i.e. temozolomide), GBM's prognosis remains poor due to its heterogeneity, recurrence and the impermeability of the blood-brain barrier (BBB).
P, Chithra +2 more
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Polymeric nanomicelles for sustained delivery of anti-cancer drugs
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2014In the first section of this paper, the existing and emerging nanotechnology-based cancer therapies--nanoparticles, drug conjugates, nanomicelles--are reviewed. In a second part, we present our original and unpublished findings on the sustained release of anti-cancer drugs such as paclitaxel, doxorubicin and camptothecin using block copolymer micelles [
Roubeena, Jeetah +2 more
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Preparation, characterization, and performance analysis of starch-based nanomicelles
International Journal of Biological Macromolecules, 2020A novel amphiphilic starch-based polymer carrier (R-St-PEG; R = hexadecyl, St = starch, PEG = polyethylene glycol) was prepared using tapioca starch. It was then applied as an effective carrier for encapsulated drug, and used for sustained drug release.
Zongliang, Kou +6 more
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Stimulus-Responsive Targeted Nanomicelles for Effective Cancer Therapy
Nanomedicine, 2009Emerging nanotechnology has already developed various innovative nanomedicines. Nanomicelles, self-assemblies of block copolymers, are promising nanomedicines for targeted drug delivery and imaging. Stimulus-responsive targeted nanomicelles are designed to release drugs based on stimuli such as pH, temperature, redox potential, magnetism and ultrasound.
Madaswamy S, Muthu +3 more
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Progress and Prospects of Polyplex Nanomicelles for Plasmid DNA Delivery
Current Gene Therapy, 2011Plasmid DNA (pDNA)-based gene therapy is a promising strategy for treating many chronic diseases and pathological states. Using pDNA has several advantages such as the sustained synthesis of proteins and peptides in their natives form, ease of the combined use of two or more bioactive factors, and cost-effectiveness.
Keiji, Itaka, Kazunori, Kataoka
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Review of Polymeric Nanomicelles
Journal of Pharmaceutical Negative Results, 2022openaire +1 more source
Envisioning the Future: Nanomicelles Revolutionizing Ocular Drug Delivery
Pharmaceutical NanotechnologyDue to the complexities of the eye's anatomy and physiology, achieving targeted drug delivery with minimal harm to healthy eye tissues has proven to be difficult. The focus of the review is on the potential of lipid and polymer micelle-based drug delivery systems, specifically nanomicelles, to overcome these challenges and improve the absorption of ...
Chetna Modi +2 more
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