Sodium Alendronate-Modified PLGA-mPEG Nanomicelles Loaded with Rifapentine for Targeted Delivery to Bone Tissue [PDF]
Background/Objectives: The limited targeting efficiency and systemic toxicity of conventional medicine present significant challenges in the treatment of skeletal disorders, such as bone tuberculosis.
Weilin Wang +7 more
doaj +2 more sources
The ameliorative effects of curcumin nanomicelle on testicular damage in the mouse model of multiple sclerosis [PDF]
Background This study investigated the effect of curcumin nanomicelle (CUR-n) on the structure of testis tissue, the process of spermatogenesis, LH, FSH, testosterone, and oxidative stress in a model of multiple sclerosis.
Farhad Koohpeyma +6 more
core +2 more sources
Mithun Varghese Vadakkan,1 K Annapoorna,2 KC Sivakumar,3 Sathish Mundayoor,2 GS Vinod Kumar1 1Chemical Biology, 2Mycobacterium Research Group, 3Bioinformatics Facility, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India Abstract ...
Vadakkan MV +4 more
doaj +1 more source
Evaluation of the efficiency of nanomicellar formulation of fat-soluble vitamins in patients with cystic fibrosis: the study protocol for a randomized controlled trial [PDF]
Background Cystic fibrosis is an inherited disease, which is caused by the CFTR protein defects due to mutations in the CFTR gene. Along with CFTR dysfunction, exocrine pancreatic insufficiency plays a key role in persistent fat malabsorption in CF ...
Mahsa Soleimanzadeh +5 more
doaj +2 more sources
In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [PDF]
Objective(s): Due to its low toxicity and high absorbance in the range of 650 to 900 nm, indocyanine green (ICG) has garnered significant attention for its applications in photodynamic therapy (PDT) and photothermal therapy (PTT).
Shirin Jalili +5 more
doaj +2 more sources
Nanomicelles: Types, properties and applications in drug delivery [PDF]
Abstract Nanomicelles are self‐assembling nanosized (usually with particle size within a range of 10 to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell. Owing to its size, solubility, customised surface or its exposure to the environment, nanomicelles show some unique or novel characteristics, which makes ...
Anamika Bose +3 more
openaire +3 more sources
Recent Advances in Nanomicelles Delivery Systems [PDF]
The efficient and selective delivery of therapeutic drugs to the target site remains the main obstacle in the development of new drugs and therapeutic interventions. Up until today, nanomicelles have shown their prospective as nanocarriers for drug delivery owing to their small size, good biocompatibility, and capacity to effectively entrap lipophilic ...
Salah M. Tawfik +4 more
openaire +3 more sources
Sphingomyelinase-responsive nanomicelles for targeting atherosclerosis
Sphingomyelinase enzymatic activity destabilises iron oxide nanomicelles and promotes its accumulation in atherosclerosis in vivo .
María Muñoz-Hernando +5 more
openaire +4 more sources
One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine
Jing-Wen Luo, Zhi-Rong Zhang, Tao Gong, Yao Fu Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, People’s Republic of China Abstract: Our study ...
Luo JW, Zhang ZR, Gong T, Fu Y
doaj +1 more source
Controlled ocular drug delivery with nanomicelles [PDF]
Many vision threatening ocular diseases such as age‐related macular degeneration (AMD), diabetic retinopathy, glaucoma, and proliferative vitreoretinopathy may result in blindness. Ocular drug delivery specifically to the intraocular tissues remains a challenging task due to the presence of various physiological barriers.
Ravi D, Vaishya +3 more
openaire +2 more sources

