Results 41 to 50 of about 1,679 (212)

Amphiphilic photosensitizer polymer as a nanocarrier of cytotoxic molecule for carrier‐free combination therapy

open access: yesMedComm – Biomaterials and Applications, 2023
Various nanocarriers have been explored to deliver drugs for combination therapy. However, most nanocarriers are composed of inert materials without contribution for improving the cancer therapeutic effect.
Jingqi Xin   +3 more
doaj   +1 more source

Mechanochemical preparation of triptolide-loaded self-micelle solid dispersion with enhanced oral bioavailability and improved anti-tumor activity

open access: yesDrug Delivery, 2022
Triptolide (TP), a compound isolated from a Chinese medicinal herb, possesses potent anti-tumor, immunosuppressive, and anti-inflammatory properties, but was clinically limited due to its poor solubility, bioavailability, and toxicity.
Dabu Zhu   +9 more
doaj   +1 more source

Polymyxin B self-associated with phospholipid nanomicelles [PDF]

open access: yesPharmaceutical Development and Technology, 2011
Although Polymyxin B (PXB) is an effective antibiotic for Gram-negative bacterial infections, clinical use is hampered by toxicity and protein binding, which may be overcome by delivering PXB using a safe nanocarrier.To determine whether PXB self-associates with long-circulating biocompatible/biodegradable PEGylated phospholipid nanomicelles (SSM) and ...
Kenneth S, Brandenburg   +3 more
openaire   +2 more sources

Advances in BODIPY Derivatives for Antibacterial Phototherapy

open access: yesAngewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv   +9 more
wiley   +2 more sources

Preventive effect of novel nanomicelle of silymarin on liver injury induced by carbon tetrachloride in rat

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2021
Background and Aim: Silymarin is used for the treatment of liver disease due to its hepatoprotective effects. however, the use of its extract is limited due to poor aqueous solubility and low bioavailability. This study aimed to prepare a new formulation
Yasaman Safian Isfahani   +3 more
doaj  

Preparation and properties of Pue-loaded HA-ADH-PS nanomicelles

open access: yesDesigned Monomers and Polymers, 2021
Puerarin (Pue) is the most abundant isoflavonoid in kudzu root. It has been widely used as a therapeutic agent for the treatment of cardiovascular diseases.
Huiru Wang   +7 more
doaj   +1 more source

Nanomicelle-Based Redox-Responsive Dual-Prodrug for Synergistic Breast Cancer Chemo-Immunotherapy

open access: yes, 2023
One of the challenges in antitumor therapy is the precise delivery of the therapeutic agent to cancerous cells. The delivery of chemotherapy agents can benefit from nanoformulation of prodrugs, which integrates the benefits of nanotechnology and prodrugs,
Liuwei Zhang   +21 more
core   +1 more source

COMPARATIVE EFFICACY OF 1% CURCUMIN NANOMICELLE GEL AND 2% CURCUMIN GEL FOR TREATMENT OF RECURRENT APHTHOUS STOMATITIS: A DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL [PDF]

open access: yes, 2022
Objective: Recurrent aphthous stomatitis (RAS) is a highly prevalent painful inflammatory condition. Curcumin is currently used as a medicinal herb with optimal anti–inflammatory properties for many inflammatory conditions.
Mahboubi, Arash   +6 more
core  

Preparation, evaluation and metabolites study in rats of novel amentoflavone-loaded TPGS/soluplus mixed nanomicelles

open access: yesDrug Delivery, 2020
Amentoflavone (AMF) is a kind of biflavonoids existing in Ginkgo biloba leaves. It has many biological activities, such as antioxidant, anti-inflammatory, anti-bacterial, antiviral, hypoglycemic, anti-tumor and inducing apoptosis. However, its solubility
Xue Feng   +5 more
doaj   +1 more source

Micellar Nanoformulation of Berberine to Mitigate Doxorubicin-induced Cardiotoxicity: A Cell-line Study [PDF]

open access: yesAl-Anbar Medical Journal, 2023
Background: Doxorubicin-induced cardiotoxicity (DIC) is a major complication of cancer chemotherapy. Thus, developing effective myocardial protection strategies during doxorubicin (Dox) therapy is a medical necessity.Objectives: To evaluate and compare ...
Noora Alyasari, Anwar Almzaiel
doaj   +1 more source

Home - About - Disclaimer - Privacy