Results 51 to 60 of about 1,679 (212)
Hematoporphyrin encapsulated polymeric nanomicelles
Archives of Advances in Biosciences, 2012 Nowadays, developements in nanotechnology have leeds an increased application of this newborn technology in cancer treatment. In this study, a stabilized micelle was developed to load HpD in order to be used in photodynamic treatment of cancer in an animal model. To construct micelles, Pluronic P-105 was used and stabilized to encapsulate HpD.
Barati, Amir Houshang +2 more
openaire +1 more source
New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles
Molecules, 2016 Intravenous administration of Taxotere® (a commercial form of docetaxel, DTX) leads to many problems such as hypersensitivity, hemolysis, cutaneous allergy, and patient refusal due to its prolonged injection. The oral absorption of DTX is very low due to
Atefeh Hekmat +4 more
doaj +1 more source
Pharmaceutics, 2022 Messenger RNA (mRNA) is an emerging drug modality for protein replacement therapy. As mRNA efficiently provides protein expression in post-mitotic cells without the risk of insertional mutagenesis, direct delivery of mRNA can be applied, not only as an ...
Jia Deng +7 more
doaj +1 more source
Nanomicelles potentiate histone deacetylase inhibitor efficacy in vitro. [PDF]
Cancer Nanotechnology, 2020 Abstract Background. Amphiphilic block copolymers used as nanomicelle drug carriers can effectively overcome poor drug solubility and specificity issues. Hence, these platforms have a broad applicability in cancer treatment. In this study, Pluronic F127 was used to fabricate nanomicelles containing the histone deacetylase inhibitor SAHA, which ...
S. Pisano +11 more
openaire +3 more sources
Preparation and Characterization of Nanomicelle for Ocular delivery of fluoroquinolone derivative
, 2019 Pluronic nanomicelles were prepared for Ocular delivery by incorporation of methyl alcohol as a dispersing agent and the surface was modifying by chitosan to improve the bioavailability. Nanomicelle dispersed well in solution and having a core shell-like
Verma, Navneet, Singh, Pawan
core +1 more source
, 2021 We report on hybrid nanomicelle-polymer inserts for improved delivery of cyclosporine A (CyA) to the surface of the eye. Hybrid inserts containing a nanomicellar formulation were prepared by the solvent casting method; their characteristics, in vitro ...
Chipala E. +8 more
core +1 more source
Iraqi Journal of Pharmaceutical SciencesThe present work aims to formulate carvedilol as nanomicelle and study variables effect on the particle size of nanomicelle, and on the entrapment efficiency (EE%).
Noor Mohammed Dawood Yahia +3 more
doaj +1 more source
Development of functional docetaxel nanomicelles for treatment of brain glioma [PDF]
Artificial Cells, Nanomedicine, and Biotechnology, 2018 The efficacy of anticancer drugs is rather limited in the treatment of brain glioma due to the hindrance of the blood-brain barrier (BBB). Herein, we reported an easy formulation of functional docetaxel nanomicelles for the treatment of brain glioma using a graft copolymer soluplus as basic material through dual-modifications with a glucose-lipid ...
Rui-Jun, Ju +5 more
openaire +2 more sources
Self-Assembling Tacrolimus Nanomicelles for Retinal Drug Delivery [PDF]
Pharmaceutics, 2020 Neovascular age-related macular degeneration (AMD) is characterized by an increase in reactive oxygen species (ROS) and pro-inflammatory cytokines in the retinal pigment epithelium cells. The primary purpose of this study was the development of a clear, tacrolimus nanomicellar formulation (TAC-NMF) for AMD. The optimized formulation had a mean diameter
Vrinda Gote +3 more
openaire +3 more sources
, 2022 Nanoparticle drug delivery systems have drawn considerable attention worldwide due to their unique characteristics and advantages in anticancer drug delivery.
Xueping Liu (810649) +8 more
core +1 more source