Results 41 to 50 of about 1,217,458 (328)

Nanoparticle vaccines

open access: yesVaccine, 2014
Nanotechnology increasingly plays a significant role in vaccine development. As vaccine development orientates toward less immunogenic "minimalist" compositions, formulations that boost antigen effectiveness are increasingly needed. The use of nanoparticles in vaccine formulations allows not only improved antigen stability and immunogenicity, but also ...
Zhao, Liang   +6 more
openaire   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Modular stimuli-responsive hydrogel sealants for early gastrointestinal leak detection and containment

open access: yesNature Communications, 2022
Digestive surgical leaks manifesting days after a successful surgery can lead to severe complications and affect healthcare worldwide. Here, the authors address the problem holistically with a hydrogel patch capable of sealing tissues, while detecting ...
Alexandre H. C. Anthis   +11 more
doaj   +1 more source

Graphdiyne as a Promising Substrate for Stabilizing Pt Nanoparticle Catalyst

open access: yes, 2015
At present, Pt nanoparticle catalysts in fuel cells suffer from aggregation and loss of chemical activity. In this work, graphdiyne, which has natural porous structure, was proposed as substrate with high adsorption ability to stabilize Pt nanoparticles.
Lin, Zheng-Zhe
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Stretchable conductive nanocomposite based on alginate hydrogel and silver nanowires for wearable electronics

open access: yesAPL Materials, 2019
Wearable electronic devices are used to perform various electronic functions on the human skin, and their mechanical softness while maintaining high performances is critical. Therefore, there is a need to develop novel materials with outstanding softness
Chanhyuk Lim   +5 more
doaj   +1 more source

Machine Learning Classification Model to Label Sources Derived from Factor Analysis Receptor Models for Source Apportionment

open access: yesAerosol and Air Quality Research, 2023
Factor analysis (FA) receptor models are widely used for source apportionment (SA) due to their ability to extract the source contribution and profile from the data.
Vikas Kumar   +3 more
doaj   +1 more source

Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies

open access: yes, 2007
DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable ...
Harris, Nolan C., Kiang, Ching-Hwa
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Effect of crosslinker length on the elastic and compression modulus of poly(acrylamide) nanocomposite hydrogels [PDF]

open access: yes, 2017
Polymer hydrogelshave shown to exhibit improved properties upon the addition of nanoparticles; however, the mechanical underpinnings behind these enhancements have not been fully elucidated.
Asuri, Prashanth   +2 more
core   +1 more source

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