Results 121 to 130 of about 65,196 (347)

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

An exploratory study on the application of nanopore sequencing for detecting Mycobacterium tuberculosis drug resistance in respiratory specimens

BMC Pulmonary Medicine
Background This study aimed to evaluate the diagnostic efficacy of nanopore sequencing for Mycobacterium tuberculosis (MTB) drug resistance in respiratory specimens from pulmonary tuberculosis (PTB) patients.
Niansa Wei, Feiyi Du, Wenjuan Nie, Yingxing Nong, Yanrong Lin, Aichun Huang, Shaoyong Xi, Yiyi Lan, Xiaoyang Luo, Shixiong Yang, Qingdong Zhu   +10 more
doaj   +1 more source

Coarse-grained simulation of polymer translocation through an artificial nanopore

, 2003
The translocation of a macromolecule through a nanometer-sized pore is an interesting process with important applications in the development of biosensors for single--molecule analysis and in drug delivery and gene therapy.
Glaser, Matthew A., Lansac, Yves, Maiti, Prabal K.   +2 more
core   +1 more source

Nanopore Sequencing Technology in Oral Oncology: A Comprehensive Insight

, 2022
Shankargouda Patil, Dominic Augustine, SV Sowmya, Vanishri C. Haragannavar, Neethi Gujjar, Afrah Yousef, Suman Kashyap   +6 more
openalex   +1 more source

ZIF‐67‐Confined Pd Single‐Atom Catalysts Implanted Into Polydopamine‐Modified Bamboo Microchannels for Robust Continuous‐Flow Hydrogenation

Advanced Science, EarlyView.
The report presents a facile room‐temperature method to stabilize Pd single‐atom catalysts within ZIF‐67 crystals during their formation. Despite an ultralow Pd loading (0.0014 wt%), the catalytic microreactor, featuring atomically dispersed Pd‐N4 sites in ZIF‐67, demonstrates superior robustness and maximized Pd utilization, significantly ...
Sisi Yao, Jiawei Han, Wenjun Zhang, Dengkang Guo, Shenjie Han, Yun Lu, Jingpeng Li   +6 more
wiley   +1 more source

PRONAME: a user-friendly pipeline to process long-read nanopore metabarcoding data by generating high-quality consensus sequences

Frontiers in Bioinformatics
BackgroundThe study of sample taxonomic composition has evolved from direct observations and labor-intensive morphological studies to different DNA sequencing methodologies.
Benjamin Dubois, Mathieu Delitte, Salomé Lengrand, Claude Bragard, Anne Legrève, Frédéric Debode   +5 more
doaj   +1 more source

Nanopore sequencing in human genetic studies: application to structural variant detection [PDF]

, 2019
Background: Nanopore sequencing is a recent technology which allows direct real-time sequencing of DNA or RNA molecules and production of read lengths as long as the size of the original fragments.
Silva, Catarina, Vieira, Luís
core  

Nanopore sequencing identifies a higher frequency and expanded spectrum of mitochondrial DNA deletion mutations in human aging [PDF]

, 2023
Amy R. Vandiver, Austin N. Hoang, Allen Herbst, Cathy C. Lee, Judd M. Aiken, Debbie McKenzie, Michael A. Teitell, Winston Timp, Jonathan Wanagat   +8 more
openalex   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Nanopore Sequencing Technology: A Reliable Method for Pathogen Diagnosis in Elderly Patients with Community-Acquired Pneumonia

Infection and Drug Resistance
Xiyue Zhang,1,* Jian Ye,2,* Limin Wang,1 Liuhai Zhang,1 Liusheng Wang,1 Hualiang Jin1 1Department of Respiratory Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China;
Zhang X, Ye J, Wang L, Zhang L, Wang L, Jin H   +5 more
doaj