Results 201 to 210 of about 998,588 (389)

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, EarlyView.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Scalable Platform Enabling Reservoir Computing With Nanoporous Oxide Memristors for Image Recognition and Time Series Prediction

Advanced Intelligent Systems, EarlyView.
The approach of physical in materia computing incorporates parallel computing within the medium itself. A scalable and energy‐efficient, oxide‐based computational platform is realized in form of a nanoporous network of volatile niobium oxide memristors sandwiched between top and bottom metallic electrodes, and then tested for prediction and ...
Joshua Donald, Ben A. Johnson, Amir Mehrnejat, Alex Gabbitas, Arthur G. T. Coveney, Alexander G. Balanov, Sergey Savel’ev, Pavel Borisov   +7 more
wiley   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, EarlyView.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

Nanopore sequencing and its application to the study of microbial communities

, 2021
Laura Ciuffreda, Hector Rodríguez‐Pérez, Carlos Flores   +2 more
openalex   +1 more source

Novel MYL1 Intron Variant With Expanded Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington, Marie Balslev‐Harder, Thomas Krag, Thomas van Overeem Hansen, Camilla Bernt Wulff, Ulrik Lausten‐Thomsen, Tina Duelund Hjortshøj, Elsebet Østergaard   +7 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

ModPhred: an integrative toolkit for the analysis and storage of nanopore sequencing DNA and RNA modification data [PDF]

, 2021
Leszek P. Pryszcz, Eva Maria Novoa
openalex   +1 more source

Nanopore-based consensus sequencing enables accurate multimodal tumor cell-free DNA profiling [PDF]

Li‐Ting Chen, Myrthe Jager, Dàmi Rebergen, Geertruid J. Brink, Tom van den Ende, Willem Vanderlinden, Pauline J. Kolbeck, Marc Pagès-Gallego, Ymke van der Pol, Nicolle Besselink, Norbert Moldován, Nizar Hami, Wigard P. Kloosterman, Hanneke W. M. van Laarhoven, Florent Moulière, Ronald P. Zweemer, Jan Lipfert, Sarah Derks, Alessio Marcozzi, Jeroen de Ridder   +19 more
openalex   +1 more source

A Rapid Drug Resistance Genotyping Workflow for Mycobacterium tuberculosis, Using Targeted Isothermal Amplification and Nanopore Sequencing

, 2021
Harriet D. Gliddon, Dan Frampton, Vanisha Munsamy, Jude Heaney, Thomas Pataillot-Meakin, Eleni Nastouli, Alexander S. Pym, Adrie J. C. Steyn, Deenan Pillay, Rachel A. McKendry   +9 more
openalex   +1 more source

Evaluation of real-time nanopore sequencing for Salmonella serotype prediction

, 2020
Feng Xu, Chongtao Ge, Hao Luo, Shaoting Li, Martin Wiedmann, Xiangyu Deng, Guangtao Zhang, Abigail Stevenson, Robert C. Baker, Silin Tang   +9 more
openalex   +1 more source