Results 211 to 220 of about 30,309 (268)
Site-specific post-translational modification detection by polar charged engineered MspA nanopores. [PDF]
Lin S +6 more
europepmc +1 more source
Bioinformatic and computational biophysics tools for nanopore engineering: a review from standard approaches to machine learning advancements. [PDF]
Reccia M +5 more
europepmc +1 more source
Nanopore-Based Profiling of PEGylation in Nucleic Acid Therapeutics. [PDF]
Patiño Guillén G +5 more
europepmc +1 more source
Chemically Modified Solid-State Nanopores
Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used to fabricate synthetic nanopores in thin solid-state membranes with subnanometer resolution.
Amit Meller, Meni Wanunu
exaly +2 more sources
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Nanopore sequencing technology: nanopore preparations
Trends in Biotechnology, 2007For the past decade, nanometer-scale pores have been developed as a powerful technique for sensing biological macromolecules. Various potential applications using these nanopores have been reported at the proof-of-principle stage, with the eventual aim of using them as an alternative to de novo DNA sequencing.
Minsoung, Rhee, Mark A, Burns
openaire +2 more sources
Analytical Chemistry, 2004
The fabrication and electrochemical characterization of truncated cone-shaped nanopore electrodes are reported. A nanopore electrode is a Pt disk electrode embedded at the bottom of a conical pore, the circular orifice of the pore having nanometer dimensions.
Bo, Zhang, Yanhui, Zhang, Henry S, White
openaire +2 more sources
The fabrication and electrochemical characterization of truncated cone-shaped nanopore electrodes are reported. A nanopore electrode is a Pt disk electrode embedded at the bottom of a conical pore, the circular orifice of the pore having nanometer dimensions.
Bo, Zhang, Yanhui, Zhang, Henry S, White
openaire +2 more sources
DNA and Cell Biology, 2004
A cheminformatics method is described for classification, and biophysical examination, of individual molecules. A novel molecular detector is used--one based on current blockade measurements through a nanometer-scale ion channel (alpha-hemolysin). Classification results are described for blockades caused by DNA molecules in the alpha-hemolysin nanopore
Stephen, Winters-Hilt, Mark, Akeson
openaire +2 more sources
A cheminformatics method is described for classification, and biophysical examination, of individual molecules. A novel molecular detector is used--one based on current blockade measurements through a nanometer-scale ion channel (alpha-hemolysin). Classification results are described for blockades caused by DNA molecules in the alpha-hemolysin nanopore
Stephen, Winters-Hilt, Mark, Akeson
openaire +2 more sources
DNA Translocation through Graphene Nanopores
We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter.
Zhuang Minghao +2 more
exaly +2 more sources
Fluorescence biosensing in nanopores
2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009Hydrated nanopores offer a unique environment for studying biological molecules under controlled conditions and fabricating sensors using fluorescence. Silica nanopores for example are non-toxic, biologically and optically compatible with protein, and can be easily synthesized to entrap protein and exclude potentially interfering macromolecules, while ...
Karolin, Jan +4 more
openaire +4 more sources
Nature Methods, 2012
Voltage-driven and enzyme-regulated control allows precise ratcheting of a DNA strand in and out of a nanopore.
openaire +2 more sources
Voltage-driven and enzyme-regulated control allows precise ratcheting of a DNA strand in and out of a nanopore.
openaire +2 more sources

