Results 211 to 220 of about 30,309 (268)

Nanopore-Based Profiling of PEGylation in Nucleic Acid Therapeutics. [PDF]

open access: yesJ Am Chem Soc
Patiño Guillén G   +5 more
europepmc   +1 more source

Chemically Modified Solid-State Nanopores

open access: yesNano Letters, 2007
Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used to fabricate synthetic nanopores in thin solid-state membranes with subnanometer resolution.
Amit Meller, Meni Wanunu
exaly   +2 more sources
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Nanopore sequencing technology: nanopore preparations

Trends in Biotechnology, 2007
For the past decade, nanometer-scale pores have been developed as a powerful technique for sensing biological macromolecules. Various potential applications using these nanopores have been reported at the proof-of-principle stage, with the eventual aim of using them as an alternative to de novo DNA sequencing.
Minsoung, Rhee, Mark A, Burns
openaire   +2 more sources

The Nanopore Electrode

Analytical Chemistry, 2004
The fabrication and electrochemical characterization of truncated cone-shaped nanopore electrodes are reported. A nanopore electrode is a Pt disk electrode embedded at the bottom of a conical pore, the circular orifice of the pore having nanometer dimensions.
Bo, Zhang, Yanhui, Zhang, Henry S, White
openaire   +2 more sources

Nanopore Cheminformatics

DNA and Cell Biology, 2004
A cheminformatics method is described for classification, and biophysical examination, of individual molecules. A novel molecular detector is used--one based on current blockade measurements through a nanometer-scale ion channel (alpha-hemolysin). Classification results are described for blockades caused by DNA molecules in the alpha-hemolysin nanopore
Stephen, Winters-Hilt, Mark, Akeson
openaire   +2 more sources

DNA Translocation through Graphene Nanopores

open access: yesNano Letters, 2010
We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter.
Zhuang Minghao   +2 more
exaly   +2 more sources

Fluorescence biosensing in nanopores

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009
Hydrated nanopores offer a unique environment for studying biological molecules under controlled conditions and fabricating sensors using fluorescence. Silica nanopores for example are non-toxic, biologically and optically compatible with protein, and can be easily synthesized to entrap protein and exclude potentially interfering macromolecules, while ...
Karolin, Jan   +4 more
openaire   +4 more sources

A nanopore workhorse

Nature Methods, 2012
Voltage-driven and enzyme-regulated control allows precise ratcheting of a DNA strand in and out of a nanopore.
openaire   +2 more sources

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