Results 31 to 40 of about 30,309 (268)

Boron nitride nanopores: Highly sensitive DNA single-molecule detectors

open access: yes, 2013
The first electronic measurement of DNA translocation through ultrathin BN nanopores is demonstrated. BN nanopores show much higher detection sensitivity compared with SiN nanopores. BN has a spatial resolution as graphene.
Zhao, Qing   +11 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

ELECTRICAL NOISES REDUCTION IN NANOPORES EXPERIMENTS BASED ON CONSENSUS FILTER [PDF]

open access: yesQuímica Nova
Nanopore has developed into an indispensable tool for single molecules experiments, where useful information about the characteristics of DNA/RNA can be obtained from the flowing of ionic current elicited by individual molecules as they traverse a single
Bingyong Yan   +3 more
doaj   +2 more sources

Solid-state nanopores: a new platform for DNA biomarker discovery [PDF]

open access: yes, 2014
Solid-state (SS) nanopores emerged as a molecular detection platform in 2001, offering many advantages over their biological counterparts, α-hemolysin nanopores (α-HL).
Marshall, Michael M.   +1 more
core  

Fabrications, Applications and Challenges of Solid-state Nanopores: A Mini Review

open access: yes, 2016
Nanopore sensors are expected to be one of the most promising next generation sequencing technologies, with label-free, amplification-free and high-throughput fea‐ tures, as well as rapid detections and low cost.
Weiwei Cui   +5 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Voltage dependent properties of DNA origami nanopores

open access: yes, 2014
We show DNA origami nanopores that respond to high voltages by a change in conformation on glass nanocapillaries. Our DNA origami nanopores are voltage sensitive as two distinct states are found as a function of the applied voltage.
Thacker, Vivek V.   +4 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Photocatalytic properties of TiO2 nanostructures of different morphology modified with various modifiers; pp. 168-177 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2019
Synthesis of TiO2 nanotube coatings, nanoporous coatings, and nanofibres by using titanium anodizing, microplasma electrolytic oxidation, and microwave-assisted hydrothermal synthesis in different regimes was studied.
Reinis Drunka   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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