Results 141 to 150 of about 8,530 (211)

Design and optimization of intranasal aripiprazole-loaded nanostructured lipid carriers for enhanced brain targeting in schizophrenia: in vitro and ex vivo evaluation. [PDF]

Sci Rep
Rahamathulla M, Bindiya R, Venkatesh MP, Pai DR, Harshith HS, Ghazwani M, Farhana SA, Buddhadev SS, Ahmed MM, Pasha I.   +9 more
europepmc   +1 more source

Machine learning‐driven advances in carbon‐based quantum dots: Opportunities accompanied by challenges

Responsive Materials, EarlyView.
Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen, Siwei Yang, Xiangqian Cui, Ziheng Liu, Hang Wang, Yongqiang Li, Peng He, Miao Wang, Guqiao Ding   +8 more
wiley   +1 more source

Surfactant Ratio-Driven Modulation of Caffeine Loading and Release in <i>Nigella sativa</i> Oil Nanostructured Lipid Carriers. [PDF]

ACS Omega
Damayanti NI, Khong NMH, Liew CV, Chutoprapat R.   +3 more
europepmc   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

Formulation Optimization of Sinomenine-Loaded Nanostructured Lipid Carriers Based on Molecular Dynamics Simulations and Evaluation of Pharmacological Efficacy in Rheumatoid Arthritis. [PDF]

Int J Mol Sci
Lin X, Ding X, Zou Y, Sheng M, Li J, Xiao Y, Xu J, Li J, Wang L, Xu W.   +9 more
europepmc   +1 more source

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

Small, EarlyView.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi, Haikun Liu, Ahmed Refaat, Hung Nguyen, Anne Nguyen, Kaiting Miao, Yuyang Song, Sylvain Trépout, Rico F. Tabor, Liliana de Campo, Karlheinz Peter, Mark Louis P. Vidallon, Xiaowei Wang   +12 more
wiley   +1 more source

Plant derived extract loaded nanostructured lipid carriers with enhanced oral delivery for the treatment of acute inflammation. [PDF]

Sci Rep
Lee EY, Choi J, Kim YM, Yang K, Jang AY, Shin HK, Kim HR, Nam K, Hwang JK, Park J, Park WJ, Roh YH.   +11 more
europepmc   +1 more source

Lipid Tail Length Determines Nano‐Bio Interactions of Peptide Amphiphile Nanostructures

Small, EarlyView.
This work demonstrates that self‐assembled peptide amphiphiles (PAs) can disassemble in circulation and reassemble with blood biomolecules. While PAs with short, less hydrophobic lipid modifications mainly bind to albumin, increasing lipid hydrophobicity shifts binding to lipoproteins.
Karla Bonic, Morgan R. Stewart, Li Xiang, Kailin Mooney, Randall Armstrong, Sadik Esener, Jared M. Fischer, Adem Yildirim   +7 more
wiley   +1 more source

Anticancer Activity of Phospholipid-Dexibuprofen Conjugates Loaded in Nanostructured Lipid Carriers. [PDF]

Int J Nanomedicine
Thiruchenthooran V, Świtalska M, Maciejewska G, Palko-Łabuz A, Bonilla-Vidal L, Espina M, Luisa Garcia M, Wietrzyk J, Souto EB, Sánchez-López E, Gliszczyńska A.   +10 more
europepmc   +1 more source

Cellulose Acetate Fibers With Infiltrated ZnO Nanocrystals: Activation of Antibacterial Properties Against Acne vulgaris by Oxygen Plasma Treatment

Small, EarlyView.
We present biodegradable cellulose acetate fibers infiltrated with ZnO nanocrystals for Acne treatment. Fibers produced by centrifugal spinning were vapor‐phase infiltrated to contain uniform ZnO nanocrystals. Oxygen plasma treatment enhanced the fibers´ wettability.
Martina Rihova, Denisa Fenclova, Pavan Kumar Chennam, Aniket Mukherjee, David Pavlinak, Susan Azpeitia, Kristyna Cihalova, Miloslav Pouzar, Kaushik Baishya, Lenka Zajíčková, Zbynek Heger, Mato Knez, Jan M. Macak   +12 more
wiley   +1 more source