Results 11 to 20 of about 964,330 (278)

Preclinical Evaluation of Lipid-Based Nanosystems [PDF]

Pharmaceutics, 2021
The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva, José Manuel Sousa Lobo   +1 more
doaj   +3 more sources

Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers.
Ni Luh Dewi Aryani, Siswandono, Wdji Soeratri, Dian Yulyandani Putri, Pingky Dwi Puspitasarini   +4 more
doaj   +4 more sources

Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect [PDF]

International Journal of Nanomedicine, 2013
Heshu Sulaiman Rahman,1–3 Abdullah Rasedee,1,2 Chee Wun How,2 Ahmad Bustamam Abdul,2 Nazariah Allaudin Zeenathul,1,2 Hemn Hassan Othman,1 Mohamed Ibrahim Saeed,2 Swee Keong Yeap21Department of Microbiology and Pathology, Faculty of Veterinary ...
Rahman HS, Rasedee A, How CW, Abdul AB, Zeenathul NA, Othman HH, Saeed MI, Yeap SK   +7 more
doaj   +3 more sources

Nanostructured Lipid Carriers as Promising Delivery Systems for Plant Extracts: The Case of Silymarin [PDF]

Applied Sciences, 2018
Background: Silymarin is the extract from seeds of Silybum marianum L. Gaertn. and it has been used for decades as hepatoprotectant. Recently, it has been proposed to be beneficial in type 2 diabetes patients. However, silymarin is a poorly water soluble
Vieri Piazzini, Beatrice Lemmi, Mario D’Ambrosio, Lorenzo Cinci, Cristina Luceri, Anna Rita Bilia, Maria Camilla Bergonzi   +6 more
doaj   +2 more sources

Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration

International Journal of Nanomedicine, 2013
Siddig Ibrahim Abdelwahab,1 Bassem Yousef Sheikh,2 Manal Mohamed Elhassan Taha,1 Chee Wun How,3 Rasedee Abdullah,3 Umar Yagoub,1 Rashad El-Sunousi,1 Eltayeb EM Eid31Medical Research Centre, Jazan University, Jazan, Saudi Arabia; 2Department of Surgery ...
Abdelwahab SI, Sheikh BY, Taha MME, How CW, Abdullah R, Yagoub U, El-Sunousi R, Eid EEM   +7 more
doaj   +1 more source

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]

Advanced Pharmaceutical Bulletin, 2015
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri, Hadi Valizadeh, Parvin Zakeri-Milani   +2 more
doaj   +3 more sources

A Comprehensive Review on Nanostructured Lipid Carriers

Journal of Drug Delivery and Therapeutics
Nanostructured lipid carriers (NLCs) mark a pivotal evolution in lipid-based drug delivery, surpassing the constraints of solid lipid nanoparticles (SLNs) to optimize therapeutic performance. Formulated with a mix of solid and liquid lipids, NLCs disrupt the rigid crystalline structure of SLNs, facilitating enhanced drug encapsulation, greater ...
R Prema, M Prabhakaran, M Meenakshi, C Sankar   +3 more
openaire   +2 more sources

Encapsulation of cannabinoid drugs in nanostructured lipid carriers

European Journal of Pharmaceutics and Biopharmaceutics, 2016
This study describes the development and optimization of a method to encapsulate the potent and expensive cannabinoids drugs in nanostructured lipid carriers; namely, URB597, AM251 and rimonabant have been considered. NLC production by melt and ultrasonication protocol has been specifically designed to optimize nanoparticle recovery and drug ...
ESPOSITO, Elisabetta, Drechsler, Markus, CORTESI, Rita, NASTRUZZI, Claudio   +3 more
openaire   +4 more sources

Revealing Changes in Celecoxib Nanostructured Lipid Carrier’s Bioavailability Using Hyaluronic Acid as an Enhancer by HPLC-MS/MS [PDF]

Drug Design, Development and Therapy
Yi Zhu,1,2,* Meiling Chen,3,* Chuangzan Yang,1,2 Geng Lu,1,2 Sa Huang,1,2 Meili Chen,3 Yufei Wang,4 Junfeng Ban1– 3 1Guangdong Pharmaceutical University, Guangzhou, People’s Republic of China; 2The Innovation Team for Integrating Pharmacy with ...
Zhu Y, Chen M, Yang C, Lu G, Huang S, Chen M, Wang Y, Ban J   +7 more
doaj   +1 more source

Difenoconazole-Loaded Nanostructured Lipid Carriers: Preparation, Characterization, and Evaluation [PDF]

Pharmaceuticals
Background/Objectives: Difenoconazole (DFC) is a broad-spectrum fungicide. However, its application is limited due to poor aqueous solubility. Drugs with low solubility can be better absorbed using nanostructured lipid carriers (NLCs).
Yinghong Li, Hu Zhang, Tingting Meng, Yuqin Zhou, Beilei Zhou, Shihan Du, Hong Yuan, Fuqiang Hu   +7 more
doaj   +2 more sources