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The Effects of Solid and Liquid Lipids on the Physicochemical Properties of Nanostructured Lipid Carriers [PDF]
Journal of Pharmaceutical Sciences, 2021 The aim of this work was to identify from a review of current literature the effects of lipids used in the development of Nanostructured Lipid Carriers (NLCs) on the physicochemical properties of the resulting formulation. The size of the solid lipid, affected by the molecular weight and the complexity of the structure, tends to affect the particle ...
Maria Apostolou +3 more
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Data in Brief, 2019 Nanostructured lipid carriers (NLCs), the second generation of lipid nanoparticles could enhance the drug loading capacity and minimize the drug expulsion during storage [1,2]. They are prepared from mixtures of solid and liquid lipids [3,4]. The article
Van-An Duong +3 more
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Applied Sciences, 2018 Background: Silymarin is the extract from seeds of Silybum marianum L. Gaertn. and it has been used for decades as hepatoprotectant. Recently, it has been proposed to be beneficial in type 2 diabetes patients. However, silymarin is a poorly water soluble
Vieri Piazzini +6 more
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Biodistribution of nanostructured lipid carriers: A tomographic study
European Journal of Pharmaceutics and Biopharmaceutics, 2015 This study describes the preparation, characterization, and biodistribution of radiolabelled nanostructured lipid carriers (NLCs) especially designed for in vivo tomographic study. A preliminary formulative study was conducted in order to incorporate (99m)Tc based tracer in NLCs.
ESPOSITO, Elisabetta +11 more
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Lipid nanostructures for antioxidant delivery: a comparative preformulation study
Beilstein Journal of Nanotechnology, 2019 This investigation is a study of new lipid nanoparticles for cutaneous antioxidant delivery. Several molecules, such as α-tocopherol and retinoic acid, have been shown to improve skin condition and even counteract the effects of exogenous stress factors ...
Elisabetta Esposito +7 more
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Nanostructured Lipid Carriers: Versatile Oral Delivery Vehicle [PDF]
Future Science OA, 2016 Oral delivery is the most accepted and economical route for drug administration and leads to substantial reduction in dosing frequency. However, this route still remains a challenge for the pharmaceutical industry due to poorly soluble and permeable drugs leading to poor oral bioavailability. Incorporating bioactives into nanostructured lipid carriers (
Poonia, Neelam +3 more
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Anastrozole Loaded Nanostructured Lipid Carriers : Preparation and Evaluation
Iraqi Journal of Pharmaceutical Sciences, 2021 Anastrozole (ANZ) is considered constitute of the fourth –generation of Non–steroidal aromatase blockage, ANZ has use for hormone receptor positive breast cancer in postmenopausal women.
Alaa Abdul-Jabbar Hashim, Nawal A. Rajab
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Review article on nanoemulsions and nanostructured lipid carriers [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2018 Lipid nanoparticles, including nanoemulsions (NEs) and nanostructured lipid carriers (NLCs) are colloidal carriers with a lipid matrix that is solid at body temperature.
mamdouh ghorab +3 more
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Molecules, 2022 Breast cancer is the neoplasia of highest incidence in women worldwide. Docetaxel (DTX), a taxoid used to treat breast cancer, is a BCS-class-IV compound (low oral bioavailability, solubility and intestinal permeability). Nanotechnological strategies can
Fabiola Vieira de Carvalho +8 more
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Intranasal Drug Administration in Alzheimer-Type Dementia: Towards Clinical Applications
Pharmaceutics, 2023 Alzheimer-type dementia (ATD) treatments face limitations in crossing the blood–brain barrier and systemic adverse effects. Intranasal administration offers a direct route to the brain via the nasal cavity’s olfactory and trigeminal pathways.
Raquel Taléns-Visconti +4 more
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