Results 91 to 100 of about 4,453 (214)

Preparation and study of two kinds of ophthalmic nano-preparations of everolimus

Drug Delivery, 2019
Objective: To prepare everolimus nanoformulations and increase their solubility to suit their application in the eye. Methods: The everolimus micelles was prepared by thin film dispersion method using Tween-80 (P80) and polyoxyethylene stearate (P40S) as
Zhan Tang, Lina Yin, Yawen Zhang, Wenying Yu, Qiao Wang, Zhajun Zhan   +5 more
doaj   +1 more source

Nanosuspension-Based Drug Delivery Systems for Topical Applications

Mohamed Mahmud E Aldeeb,1,2,* Gofarana Wilar,3,* Cecep Suhandi,1,* Khaled M Elamin,4,* Nasrul Wathoni1,* 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, 45363 ...
Aldeeb MME, Wathoni N, Wilar G, Elamin KM, Suhandi C   +4 more
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Formulation and Characterization of Sonchus arvensis L. Nanosuspension for Enhanced Antioxidant and Lipid-Lowering Activities

Mohamed Mahmud E Aldeeb,1– 3 Gofarana Wilar,4 Cecep Suhandi,1,2 Ahmed Fouad Abdelwahab Mohammed,5 Ali El-Rayyes,6 Khaled M Elamin,7 Nasrul Wathoni2 1Doctoral Program of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, 45363, Indonesia;
Aldeeb MME, El-Rayyes A, Wathoni N, Wilar G, Mohammed AFA, Elamin KM, Suhandi C   +6 more
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NANOSUSPENSION TECHNOLOGY: A INNOVATIVE SLANT FOR DRUG DELIVERY SYSTEM AND PERMEABILITY ENHANCER FOR POORLY WATER SOLUBLE DRUGS

, 2015
Nanosuspension contains submicron colloidal dispersion of pharmaceutical active ingredient particles in a liquid phase stabilized by surfactants. The poor water solubility of drugs is major problem for drug formulation.
Patel, Bhavesh, Shah, Dhiren P., Shah, Chainesh   +2 more
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Sesamol-Loaded PLGA Nanosuspension for Accelerating Wound Healing in Diabetic Foot Ulcer in Rats

International Journal of Nanomedicine, 2020
Karthik Gourishetti,1 Raghuvir Keni,1 Pawan Ganesh Nayak,1 Srinivas Reddy Jitta,2 Navya Ajitkumar Bhaskaran,2 Lalit Kumar,2 Nitesh Kumar,1 Nandakumar Krishnadas,1 Rekha Raghuveer Shenoy1 1Department of Pharmacology, Manipal College of Pharmaceutical ...
Gourishetti K, Keni R, Nayak PG, Jitta SR, Bhaskaran NA, Kumar L, Kumar N, Krishnadas N, Shenoy RR   +8 more
doaj  

Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by oridonin nanosuspension

, 2010
The mechanism for anti-tumor activity of oridonin (ORI) nanosuspension, prepared by the high pressure homogenization method, was studied using MCF-7 human breast carcinoma cells in vitro.
Qi, Xiao-Li, Hai-Yan Lou, Qiang Zhang, Lou, Hai-Yan, Zhang, Qiang, Wang, Yan-Cai, Wang, Fei-Hu, Tian, Ke-Li, Duan, Cun-Xian, Fei-Hu Wang, Cun-Xian Duan, Yue Liu, Xiao-Li Qi, Feng, Fei-Fei, Liu, Yue, Zhang, Dian-Rui, Ke-Li Tian, Yan-Cai Wang, Fei-Fei Feng, Le-Jiao Jia, Jia, Le-Jiao, Dian-Rui Zhang   +21 more
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A novel albumin wrapped nanosuspension of meloxicam to improve inflammation-targeting effects

, 2018
Qi Li,1 Fen Chen,2 Yun Liu,1 Shihui Yu,1 Xiumei Gai,1 Mingzhu Ye,1 Xinggang Yang,1 Weisan Pan1 1Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China; 2Key Laboratory of ...
Ye M, Yang X, Liu Y, Gai X, Pan W, Yu S, Chen F, Li Q   +7 more
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Preparation and Evaluation of Lercanidipine HCl Nanosuspension to Improve the Dissolution Rate

Iraqi Journal of Pharmaceutical Sciences
                 Lercanidipine HCl, a third-generation calcium channel blocker, blocks calcium entry into smooth muscle L-type calcium channels. This action leads to a decrease in blood pressure and induces peripheral vasodilation.
Zahraa A. Alsafar, Fatima J. Jawad
doaj   +1 more source

A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization

International Journal of Nanomedicine, 2016
Navya Sree Kola Srinivas,1 Ruchi Verma,2 Girish Pai Kulyadi,1 Lalit Kumar1 1Department of Pharmaceutics, 2Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India Abstract ...
Kola Srinivas NS, Verma R, Pai Kulyadi G, Kumar L   +3 more
doaj  

Preparation, characterization, and evaluation of azoxystrobin nanosuspension produced by wet media milling

, 2018
To improve the bioavailability of the poorly water-soluble fungicide, an azoxystrobin nanosuspension was prepared by the wet media milling method. Due to their reduced mean particle size and polydispersity index, 1-Dodecanesulfonic acid sodium salt and ...
Xiang Zhao, Haixin Cui, Junwei Yao, Guoqiang Liu, Jinming Gao, Yan Wang, Zhanghua Zeng, Dongsheng Yang, Bo Cui, Changjiao Sun   +9 more
core   +1 more source