Results 71 to 80 of about 4,959 (213)

In vitro dissolution and bioavailability study of furosemide nanosuspension prepared using design of experiment (DoE)

Saudi Pharmaceutical Journal, 2019
Background: Nanotechnology can offer the advantages of increasing solubility and bioavailability of delivering drugs like Furosemide. The aim of the current study is to investigate the in vitro and in vivo performance of furosemide nanosuspensions ...
Mohammad H. Shariare, Mohammad A. Altamimi, Akbar L. Marzan, Rahnuma Tabassum, Basarat Jahan, Hasan M. Reza, Mahbubur Rahman, G.U. Ahsan, Mohsin Kazi   +8 more
doaj   +1 more source

Advancing gambogic acid for translational oncology: Redox–proteostasis collapse, multidrug resistance reversal, nanodelivery and biomarker‐guided development

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel, Kajal Gurow, Geetanjali Mehara, Priyanka Kriplani, Neelam M. Patel, Abhay Sharma, Deeksha Singh, Atamjit Singh, Suchi Dave, Bhawani Singh, Lashyn N. Kiyekbayeva, William N. Setzer, Javad Sharifi‐Rad, Cheryl Grace Pratiwi Rumahorbo, Daniela Calina   +14 more
wiley   +1 more source

Nanosuspensions: a promising drug delivery strategy [PDF]

Journal of Pharmacy and Pharmacology, 2004
Abstract Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions.
V B, Patravale, Abhijit A, Date, R M, Kulkarni   +2 more
openaire   +2 more sources

FORMULATION DEVELOPMENT OF IMMEDIATE RELEASE PELLETS OF TADALAFIL: SOLIDIFICATION APPROACH FOR NANOSUSPENSION: SOLIDIFICATION APPROACH FOR NANOSUSPENSION

, 2019
Objective: Nanosuspension is known to enhance the saturation solubility and dissolution velocity of poorly soluble drugs owing to the increased surface area of nanosized particles.
UBGADE, SHOBHA, BAHEKAR, VIDYA, ITTADWAR, ABHAY, KILOR, VAISHALI   +3 more
core   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, Volume 11, Issue 4, Page 1095-1110, August 2026.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Long‐Acting Injectable Antiretroviral Therapies for HIV Treatment and Prevention: Clinical Pharmacology, Recent Advances and Future Opportunities

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Long‐acting (LA) antiretroviral (ARV) medications represent a significant advancement in the HIV treatment and prevention field. LA ARVs help reduce daily pill burden and thus optimize adherence, which has translated into sustained virologic suppression in persons with HIV, prevention of HIV transmission among those at risk, and improved ...
Alexandra Dunbar, Natella Rakhmanina, Justin Unternaher, Peter L. Anderson, Kristina M. Brooks   +4 more
wiley   +1 more source

Formulation And In Vivo Evaluation Of Ritonavir Nanosuspension

, 2023
Aim: Formulation and in vivo evaluation of Ritonavir nanosuspension. Objectives: To study the significance variance in the pharmacokinetic parameters of  ritonavir.
P.Bhaskar Reddy, C.K.Dhanapal, Shaik Harun Rasheed   +2 more
core   +1 more source

High‐Shear Mixing of Softwood Kraft Lignin in Aqueous Sodium Lignosulfonate: Stable Suspensions, Efficient Emulsification and Controlled Curing of Epoxy Adhesives

Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Blending sodium lignosulfonate with softwood kraft lignin generates stable, high‐consistency aqueous suspensions. The lignosulfonate efficiently coats and disperses the kraft lignin particles, producing a thick, extrudable paste. This fully bio‐based, solvent‐free approach demonstrates great potential as a sustainable wood adhesive, paving the way for ...
Federica Ferruti, Ievgen Pylypchuk, Mika H. Sipponen   +2 more
wiley   +1 more source

Increasing Possibilities of Nanosuspension

Journal of Nanotechnology, 2013
Nowadays, a very large proportion of new drug candidates emerging from drug discovery programmes are water insoluble and thus poorly bioavailable. To avoid this problem, nanotechnology for drug delivery has gained much interest as a way to improve the solubility problems. Nano refers to particles size range of 1–1000 nm. The reduction of drug particles
Kumar Bishwajit Sutradhar, Sabera Khatun, Irin Parven Luna   +2 more
openaire   +3 more sources

Formulation and Evaluation of Lamivudine Nanosuspension

, 2021
The present research aimed to develop & Evaluation of Lamivudine Nanosuspension. Lamivudine is a potent in vitro inhibitor of human immune deficiency virus belongs to the category of anti-retroviral drugs.
Hari Chandana, Guduru, Sarayu, Ballem, Sana, Shaik, Ramesh, Yerikala, Neelima, Obili   +4 more
core   +1 more source