Results 61 to 70 of about 4,453 (214)

TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley   +1 more source

Formulation and validation of Candesartan cilexetil-loaded nanosuspension to enhance solubility [PDF]

Pharmacia
The following research aimed to enhance solubility by loading candesartan cilexetil into nanosuspension. Candesartan cilexetil-loaded nanosuspension was prepared with the aid of Design-Expert® software.
Sarmad Al-Edresi, Karrar Albo Hamrah, Abulfadhel Al-Shaibani   +2 more
doaj   +3 more sources

A Design of Experiment (DoE) based approach for development and optimization of nanosuspensions of telmisartan, a BCS class II antihypertensive drug

Future Journal of Pharmaceutical Sciences, 2020
Background The present study was aimed to enhance the solubility and dissolution of BCS class II drug, telmisartan (TEM), by nanoformulation approach. Several attempts were made to develop a nanosuspension by bottom-up and top-down techniques.
E. Bhargav, G. Chaithanya Barghav, Y. Padmanabha Reddy, Chintamaneni Pavan kumar, P. Ramalingam, C. Haranath   +5 more
doaj   +1 more source

Steering and guiding light with light in a nanosuspension [PDF]

Optics Letters, 2013
We experimentally demonstrate guiding of a low-power probe beam (633 nm wavelength) by means of a light-induced waveguide generated by the self-focusing of a strong pump beam (532 nm wavelength) in an artificial nonlinear medium, constituted by a colloidal suspension of dielectric nanoparticles. We also demonstrate optical steering of the probe beam by
Terborg, Roland A., Pérez Torres, Juan, Volke-Sepulveda, Karen   +2 more
openaire   +4 more sources

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

FORMULATION DEVELOPMENT AND CHARACTERIZATION OF LYOPHILIZED FEBUXOSTAT NANOSUSPENSION

, 2022
Objective: The study aims to prepare and evaluate febuxostat nanosuspension to improve oral bioavailability. Methods: Febuxostat nanosuspension was prepared by the solvent-antisolvent method, followed by a lyophilization technique using PVP K-30 as a ...
PETHE, ANIL, DEWANI, SUNIL, VAIDYA, SUNITA, HADKE, ANKITA   +3 more
core   +1 more source

Nanosuspensions: a promising drug delivery strategy [PDF]

Journal of Pharmacy and Pharmacology, 2004
Abstract Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions.
V B, Patravale, Abhijit A, Date, R M, Kulkarni   +2 more
openaire   +2 more sources

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, Volume 13, Issue 27, 13 May 2026.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

Development and in vitro evaluation of deacety mycoepoxydiene nanosuspension

, 2011
National Basic Research Program of China (973 Program) [2009CB930300]; Major scientific and technological specialized project for Significant New Formulation of New Drugs [2009ZX09502-001]Deacety mycoepoxydiene (DM), extracted from Phomopsis sp.
Zhang, D. R., Liu, Z. P., Zhang, X. Y., Jia, L. J., Feng, F. F., Huang, Y. J., Wang, Y. C., Zhang, Q. A., Duan, C. X., Gao, X. H., Shen, Y. M., 沈月毛   +11 more
core   +2 more sources

In vitro dissolution and bioavailability study of furosemide nanosuspension prepared using design of experiment (DoE)

Saudi Pharmaceutical Journal, 2019
Background: Nanotechnology can offer the advantages of increasing solubility and bioavailability of delivering drugs like Furosemide. The aim of the current study is to investigate the in vitro and in vivo performance of furosemide nanosuspensions ...
Mohammad H. Shariare, Mohammad A. Altamimi, Akbar L. Marzan, Rahnuma Tabassum, Basarat Jahan, Hasan M. Reza, Mahbubur Rahman, G.U. Ahsan, Mohsin Kazi   +8 more
doaj   +1 more source