Results 91 to 100 of about 21,006 (329)

Recent Advances in the Bioactive Structure and Application of Single-atom Nanozymes

Nano Biomedicine and Engineering
Single-atom nanozymes have attracted much attention as a new type of high-performance nanozymes. Compared with other nanozymes, single-atom nanozymes have become the most promising candidates for naturally-occurring enzymes due to their lower cost ...
Shaofang Zhang, Xiao-Dong Zhang
doaj   +1 more source

Gold Nanozymes: From Concept to Biomedical Applications

, 2020
In recent years, gold nanoparticles have demonstrated excel‑lent enzyme‑mimicking activities which resemble those of peroxidase, oxi‑dase, catalase, superoxide dismutase or reductase.
Cao, Cuong; id_orcid, Das, Bhaskar, Elliott, Christopher, Lou-Franco, Javier, Cao, Cuong   +4 more
core   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Nanozyme-based catalytic theranostics

RSC Advances, 2020
With its diverse physical–chemical properties and highly efficient enzyme-like activities, nanozymes have been widely used in various theranostics.
Yanan Zhang, Yiliang Jin, Haixia Cui, Xiyun Yan, Kelong Fan   +4 more
openaire   +3 more sources

Electrocatalytic Nanoparticles That Mimic the Three-Dimensional Geometric Architecture of Enzymes: Nanozymes [PDF]

, 2018
Enzymes are characterized by an active site that is typically embedded deeply within the protein shell thus creating a nanoconfined reaction volume in which high turnover rates occur.
Kientz, M, Corina Andronescu, Soshan Cheong, Richard D. Tilley, Wilde, Patrick, Martin Kientz (5824400), Benedetti, Tania M, J. Justin Gooding (9046), Schuhmann, W, Tania M. Benedetti, Wordsworth, Johanna, Gooding, J Justin, Wolfgang Schuhmann (76166), Benedetti, TM, J. Justin Gooding, Andronescu, Corina, Tania M. Benedetti (5824394), Cheong, Soshan, Gooding, JJ ; https://orcid.org/, Tilley, RD ; https://orcid.org/, Schuhmann, Wolfgang, Kientz, Martin, Corina Andronescu (1731877), Cheong, S ; https://orcid.org/, Wilde, P, Johanna Wordsworth, Tilley, Richard D, Patrick Wilde, Patrick Wilde (3597032), Johanna Wordsworth (5824397), Martin Kientz, Andronescu, C, Soshan Cheong (1454845), Richard D. Tilley (378517), Wolfgang Schuhmann, Wordsworth, J   +35 more
core   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

Advanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang, Qian Cheng, Ziyi Wang, Jianwen Wei, Qun Guan, Huazhong Yu, Qingwen Zhang, Caixia Yin, Ruibing Wang   +8 more
wiley   +1 more source

Carbon-based Nanozymes: How Structure Affects Performance

Nano Biomedicine and Engineering
In the past decade, nanozymes - a unique class of nanomaterials with inherent enzyme-mimetic properties - have fascinated researchers, revealing unexpected enzyme-like activity of nanomaterials previously considered biologically inert.
Jiuyang He, Yinyin Hou, Zixia Zhang, Junying Zhang, Xiyun Yan, Kelong Fan, Minmin Liang   +6 more
doaj   +1 more source

Metal–organic framework derived nanozymes in biomedicine

, 2020
Nanozymes that integrate the advantages of both nanomaterials and natural enzymes have accumulated enormous research interest over the past decades because of the opportunity it provides to appreciate and further cultivate artificial enzymes with ...
Wang, Dongdong, Zhao, Yanli, Jana, Deblin   +2 more
core   +1 more source

Applications of nanozymes in the environment [PDF]

, 2020
Nanozymes are inorganic nanoparticles that mimic the enzyme-like properties in redox reactions, processing both unique properties of nanomaterials and a catalytic function.
Li, Wenfeng, Gadd, Geoffrey Michael, Meng, Yutong, Pan, Xiangliang   +3 more
core   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source